Assessment of Dried Blood Spots for Multi-Mycotoxin Biomarker Analysis in Pigs and Broiler Chickens.

biomarkers for exposure broiler chickens dried blood spots exposure assessment multi-mycotoxin analysis pigs toxicokinetic study

Journal

Toxins
ISSN: 2072-6651
Titre abrégé: Toxins (Basel)
Pays: Switzerland
ID NLM: 101530765

Informations de publication

Date de publication:
18 09 2019
Historique:
received: 23 08 2019
revised: 13 09 2019
accepted: 15 09 2019
entrez: 22 9 2019
pubmed: 22 9 2019
medline: 3 10 2020
Statut: epublish

Résumé

Dried blood spots (DBSs), a micro-sampling technique whereby a drop of blood is collected on filter paper has multiple advantages over conventional blood sampling regarding the sampling itself, as well as transportation and storage. This is the first paper describing the development and validation of a method for the determination of 23 mycotoxins and phase I metabolites in DBSs from pigs and broiler chickens using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The targeted mycotoxins belong to groups for which the occurrence in feed is regulated by the European Union, namely, aflatoxins, ochratoxin A and several

Identifiants

pubmed: 31540490
pii: toxins11090541
doi: 10.3390/toxins11090541
pmc: PMC6784198
pii:
doi:

Substances chimiques

Biomarkers 0
Mycotoxins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Références

Toxins (Basel). 2019 Mar 19;11(3):
pubmed: 30893895
J Pharm Biomed Anal. 2018 Jan 5;147:288-296
pubmed: 28803682
Mol Nutr Food Res. 2015 Sep;59(9):1837-43
pubmed: 26012425
J Sci Food Agric. 2013 Sep;93(12):2892-9
pubmed: 23670211
Toxins (Basel). 2017 Jul 18;9(7):
pubmed: 28718805
J Agric Food Chem. 2011 Apr 13;59(7):2980-7
pubmed: 21370870
Pediatrics. 1963 Sep;32:338-43
pubmed: 14063511
Toxins (Basel). 2019 Mar 28;11(4):
pubmed: 30925814
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2015;32(6):934-49
pubmed: 25833119
Mycotoxin Res. 2009 Jun;25(2):59-66
pubmed: 23604980
J Chromatogr B Analyt Technol Biomed Life Sci. 2016 May 1;1020:158-64
pubmed: 27046696
Toxins (Basel). 2016 Dec 06;8(12):
pubmed: 27929415
Bioanalysis. 2014;6(14):1871-4
pubmed: 25158957
Anal Bioanal Chem. 2017 May;409(13):3369-3382
pubmed: 28299415
J Agric Food Chem. 2018 Mar 7;66(9):2129-2135
pubmed: 29417821
J Agric Food Chem. 2012 Jul 25;60(29):7129-36
pubmed: 22734473
J Agric Food Chem. 2015 Oct 7;63(39):8734-42
pubmed: 26343882
J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 15;879(24):2403-15
pubmed: 21767999
Toxins (Basel). 2013 Mar 08;5(3):504-23
pubmed: 23529186
Food Chem Toxicol. 2016 Dec;98(Pt B):210-219
pubmed: 27816556
Environ Int. 2015 Nov;84:82-9
pubmed: 26233555
Int J Food Microbiol. 2003 Apr 25;82(2):173-9
pubmed: 12568757
Anal Chem. 2003 Jul 1;75(13):3019-30
pubmed: 12964746
Expert Opin Drug Metab Toxicol. 2018 Jan;14(1):1-3
pubmed: 29205069
J Chromatogr A. 2012 Sep 28;1257:74-80
pubmed: 22917981
Clin Chim Acta. 2013 Jun 25;422:54-8
pubmed: 23566929
Anal Bioanal Chem. 2011 Nov;401(9):2831-41
pubmed: 21892639

Auteurs

Marianne Lauwers (M)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. marianne.lauwers@ugent.be.
Innovad Global, Postbaan 69, 2910 Essen, Belgium. marianne.lauwers@ugent.be.

Siska Croubels (S)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. siska.croubels@ugent.be.

Siegrid De Baere (S)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. siegrid.debaere@ugent.be.

Milena Sevastiyanova (M)

Innovad Global, Postbaan 69, 2910 Essen, Belgium. m.sevastiyanova@innovad-global.com.

Eva Maria Romera Sierra (EM)

Innovad Global, Postbaan 69, 2910 Essen, Belgium. e.romera@innovad-global.com.

Ben Letor (B)

Innovad Global, Postbaan 69, 2910 Essen, Belgium. b.letor@innovad-global.com.

Christos Gougoulias (C)

Innovad Global, Postbaan 69, 2910 Essen, Belgium. C.Gougoulias@innovad-global.com.

Mathias Devreese (M)

Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Ghent University, 9820 Merelbeke, Belgium. mathias.devreese@ugent.be.

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Classifications MeSH