A combination of infrared spectroscopy and morphological analysis allows successfully identifying rare crystals and atypical urinary stones.


Journal

Annali dell'Istituto superiore di sanita
ISSN: 2384-8553
Titre abrégé: Ann Ist Super Sanita
Pays: Italy
ID NLM: 7502520

Informations de publication

Date de publication:
Historique:
entrez: 26 9 2019
pubmed: 26 9 2019
medline: 25 2 2020
Statut: ppublish

Résumé

The combination of infrared spectroscopy and morphological analysis significantly improves the urinary stone analysis. In addition to common urinary stones, it is not unusual to encounter spurious or factitious stones that, if not appropriately identified, can lead to errors in the diagnosis. In this study, we show the importance of Infrared Spectroscopy and the morphological analysis, for determining the presence of drugs crystals or atypical components in the calculi. 1041 urinary stones were analyzed by morphocostitutional analysis, in addition the rare stones were analyzed by chemical spot test analysis. Among 1041 calculi analyzed, 1018 had a known composition, 23 samples were stones with rare composition or fake urinary stones. Infrared spectroscopy (FT-IR), allows to identify, theoretically, any substance, including drug-containing calculi or calculi with unusual composition and identify false stones. This is mandatory to treat patients affected by urolithiasis with a personalized clinical approach.

Sections du résumé

BACKGROUND BACKGROUND
The combination of infrared spectroscopy and morphological analysis significantly improves the urinary stone analysis. In addition to common urinary stones, it is not unusual to encounter spurious or factitious stones that, if not appropriately identified, can lead to errors in the diagnosis. In this study, we show the importance of Infrared Spectroscopy and the morphological analysis, for determining the presence of drugs crystals or atypical components in the calculi.
METHODS METHODS
1041 urinary stones were analyzed by morphocostitutional analysis, in addition the rare stones were analyzed by chemical spot test analysis.
RESULTS RESULTS
Among 1041 calculi analyzed, 1018 had a known composition, 23 samples were stones with rare composition or fake urinary stones.
CONCLUSIONS CONCLUSIONS
Infrared spectroscopy (FT-IR), allows to identify, theoretically, any substance, including drug-containing calculi or calculi with unusual composition and identify false stones. This is mandatory to treat patients affected by urolithiasis with a personalized clinical approach.

Identifiants

pubmed: 31553311
doi: 10.4415/ANN_19_03_02
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

205-208

Auteurs

Aniello Primiano (A)

Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Silvia Persichilli (S)

Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Pietro Manuel Ferraro (PM)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy - Istituto di Medicina Interna e Geriatria, Università Cattolica del Sacro Cuore, Rome, Italy.

Angelo Minucci (A)

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Giovanni Gambaro (G)

UOC di Nefrologia e Dialisi, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.

Andrea Urbani (A)

Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Jacopo Gervasoni (J)

Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, Rome, Italy - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

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Classifications MeSH