Enterovirus D68 Subclade B3 Circulation in Senegal, 2016: Detection from Influenza-like Illness and Acute Flaccid Paralysis Surveillance.
Adolescent
Adult
Child
Child, Preschool
Disease Outbreaks
Enterovirus D, Human
/ pathogenicity
Enterovirus Infections
/ epidemiology
Female
Humans
Infant
Infant, Newborn
Influenza, Human
/ epidemiology
Male
Middle Aged
Molecular Epidemiology
/ methods
Paralysis
/ epidemiology
Phylogeny
Respiratory Tract Infections
/ epidemiology
Senegal
/ epidemiology
Virus Diseases
/ epidemiology
Young Adult
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
25 09 2019
25 09 2019
Historique:
received:
18
04
2019
accepted:
04
09
2019
entrez:
27
9
2019
pubmed:
27
9
2019
medline:
28
10
2020
Statut:
epublish
Résumé
Following the 2014 outbreak, active surveillance of the EV-D68 has been implemented in many countries worldwide. Despite subsequent EV-D68 outbreaks (2014 and 2016) reported in many areas, EV-D68 circulation remains largely unexplored in Africa except in Senegal, where low levels of EV-D68 circulation were first noted during the 2014 outbreak. Here we investigate subsequent epidemiology of EV-D68 in Senegal from June to September 2016 by screening respiratory specimens from ILI and stool from AFP surveillance. EV-D68 was detected in 7.4% (44/596) of patients; 40 with ILI and 4 with AFP. EV-D68 detection was significantly more common in children under 5 years (56.8%, p = 0.016). All EV-D68 strains detected belonged to the newly defined subclade B3. This study provides the first evidence of EV-D68 B3 subclade circulation in Africa from patients with ILI and AFP during a 2016 outbreak in Senegal. Enhanced surveillance of EV-D68 is needed to better understand the epidemiology of EV-D68 in Africa.
Identifiants
pubmed: 31554908
doi: 10.1038/s41598-019-50470-z
pii: 10.1038/s41598-019-50470-z
pmc: PMC6761155
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
13881Références
Pediatr Infect Dis J. 2019 Jan;38(1):16-21
pubmed: 30234793
Euro Surveill. 2018 Sep;23(37):
pubmed: 30229724
PLoS One. 2014 Jul 23;9(7):e102866
pubmed: 25054861
Eur J Paediatr Neurol. 2017 Nov;21(6):884-890
pubmed: 28747261
Lancet. 2015 Apr 25;385(9978):1662-71
pubmed: 25638662
J Clin Virol. 2018 Feb - Mar;99-100:91-96
pubmed: 29396353
Arch Argent Pediatr. 2017 Aug 1;115(4):364-369
pubmed: 28737865
Springerplus. 2016 Feb 24;5:158
pubmed: 27026855
PLoS One. 2014 Mar 27;9(3):e93227
pubmed: 24675982
J Microbiol Immunol Infect. 2017 Aug;50(4):411-417
pubmed: 26458357
Clin Infect Dis. 2016 Sep 15;63(6):737-745
pubmed: 27318332
Sci Rep. 2017 Apr 28;7(1):1242
pubmed: 28455514
J Gen Virol. 2012 Sep;93(Pt 9):1952-1958
pubmed: 22694903
Medicine (Baltimore). 2016 Aug;95(31):e4416
pubmed: 27495059
MMWR Morb Mortal Wkly Rep. 2017 Jul 21;66(28):758-760
pubmed: 28727681
J Clin Virol. 2017 Jul;92:39-41
pubmed: 28521212
J Clin Virol. 2017 Aug;93:40-44
pubmed: 28618288
J Microbiol Immunol Infect. 2018 Oct;51(5):688-691
pubmed: 29339008
MMWR Morb Mortal Wkly Rep. 2014 Sep 12;63(36):798-9
pubmed: 25211545
J Clin Microbiol. 2015 May;53(5):1725-6
pubmed: 25694533
Euro Surveill. 2016 Nov 17;21(46):
pubmed: 27918268
Emerg Infect Dis. 2019 Jul;25(7):1404-1407
pubmed: 31211670
MMWR Morb Mortal Wkly Rep. 2017 Aug 11;66(31):826-829
pubmed: 28796760
J Emerg Med. 2017 Jul;53(1):e19-e23
pubmed: 28412073
Emerg Infect Dis. 2019 Mar;25(3):573-576
pubmed: 30602120
MMWR Morb Mortal Wkly Rep. 2011 Sep 30;60(38):1301-4
pubmed: 21956405
PLoS Pathog. 2017 Feb 23;13(2):e1006199
pubmed: 28231269
Clin Infect Dis. 2018 Feb 10;66(5):653-664
pubmed: 29028962
Pediatr Infect Dis J. 2017 Dec;36(12):1214-1216
pubmed: 28661963
Influenza Other Respir Viruses. 2017 May;11(3):211-219
pubmed: 28122175
Euro Surveill. 2016 Nov 17;21(46):
pubmed: 27918255
Ann Am Thorac Soc. 2015 May;12(5):775-81
pubmed: 25714788
Emerg Infect Dis. 2016 Aug;22(8):1387-94
pubmed: 27434186
Lancet Infect Dis. 2016 May;16(5):e64-e75
pubmed: 26929196
Medicine (Baltimore). 2018 Sep;97(36):e11831
pubmed: 30200066
Lancet Infect Dis. 2015 Jun;15(6):671-82
pubmed: 25837569
J Med Virol. 2017 Oct;89(10):1759-1767
pubmed: 28574589
Emerg Infect Dis. 2017 Jan;23(1):140-143
pubmed: 27660916
Diagn Microbiol Infect Dis. 2016 Jun;85(2):174-6
pubmed: 27036976