[Dermatomyositis and rectal cancer: case study and literature review].

Dermatomyosite et cancer rectal: à propos d’un cas avec revue de la littérature.

Journal

The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926

Informations de publication

Date de publication:
2019
Historique:
received: 30 11 2017
accepted: 28 01 2019
entrez: 28 9 2019
pubmed: 29 9 2019
medline: 9 10 2019
Statut: epublish

Résumé

Dermatomyositis is a systemic idiopathic disease characterized by a combination of both muscle and skin symptoms. It is a paraneoplastic dermatosis. Its association with rectal cancer has been rarely described in the literature. We here report the case of a female patient with paraneoplastic dermatomyositis associated with metastatic rectal adenocarcinoma presenting with clinical symptoms commonly found in subjects with paraneoplastic dermatomyositis. Other complementary examinations (CPK test + EMG + skin biopsy) were performed which confirmed this diagnosis. The patient underwent chemotherapy, but after the second cycle, she experienced a rapid worsening of her general condition and died after some days in a state of multisystem organ failure. This study aims to highlight paraneoplastic dermatomyositis' aggressive nature and to update current knowledge on the importance of chemotherapy in the management of neoplastic dermatomyositis.

Identifiants

pubmed: 31558922
doi: 10.11604/pamj.2019.33.122.14509
pii: PAMJ-33-122
pmc: PMC6754859
doi:

Types de publication

Case Reports Journal Article Review

Langues

fre

Sous-ensembles de citation

IM

Pagination

122

Déclaration de conflit d'intérêts

Les auteurs ne déclarent aucun conflit d'intérêts.

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Auteurs

Hajar Ouahbi (H)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Meriem Benhami (M)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Lamiae Nouikh (L)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Nissrine Acharfi (N)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Awatef Kelati (A)

Service de Dermatologie, CHU Hassan II, Fès, Maroc.

Karima Oualla (K)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Zineb Benbrahim (Z)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Fatima Zahra Elmrabet (FZ)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Samia Arifi (S)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

Fatimazohra Mernissi (F)

Service de Dermatologie, CHU Hassan II, Fès, Maroc.

Nawfel Mellas (N)

Service d'Oncologie Médicale, CHU Hassan II, Fès, Maroc.

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Classifications MeSH