Selective Phenylimidazole-Based Inhibitors of the


Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
24 10 2019
Historique:
pubmed: 29 9 2019
medline: 7 7 2020
entrez: 28 9 2019
Statut: ppublish

Résumé

Proteasomes of pathogenic microbes have become attractive targets for anti-infectives. Coevolving with its human host,

Identifiants

pubmed: 31560200
doi: 10.1021/acs.jmedchem.9b01187
pmc: PMC7091493
mid: NIHMS1576710
doi:

Substances chimiques

Imidazoles 0
Proteasome Inhibitors 0
Reactive Nitrogen Species 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

9246-9253

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI070285
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI101393
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002384
Pays : United States

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Auteurs

Wenhu Zhan (W)

Department of Microbiology & Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.

Hao-Chi Hsu (HC)

Structural Biology Program , Van Andel Institute , 333 Bostwick Avenue Northeast , Grand Rapids , Michigan 49503 , United States.

Trevor Morgan (T)

Cyclofluidic Limited , Biopark Broadwater Road , Welwyn Garden City AL7 3AX , U.K.

Tierra Ouellette (T)

Department of Microbiology & Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.

Kristin Burns-Huang (K)

Department of Microbiology & Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.

Ryoma Hara (R)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Adrian G Wright (AG)

Cyclofluidic Limited , Biopark Broadwater Road , Welwyn Garden City AL7 3AX , U.K.

Toshihiro Imaeda (T)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Rei Okamoto (R)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Kenjiro Sato (K)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Mayako Michino (M)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Manoj Ramjee (M)

Cyclofluidic Limited , Biopark Broadwater Road , Welwyn Garden City AL7 3AX , U.K.

Kazuyoshi Aso (K)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Peter T Meinke (PT)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Michael Foley (M)

Tri-Institutional Therapeutics Discovery Institute , 413 East 69th Street , New York , New York 10065 , United States.

Carl F Nathan (CF)

Department of Microbiology & Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.

Huilin Li (H)

Structural Biology Program , Van Andel Institute , 333 Bostwick Avenue Northeast , Grand Rapids , Michigan 49503 , United States.

Gang Lin (G)

Department of Microbiology & Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States.

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Classifications MeSH