Tumor-infiltrating lymphocytes and CD8
CD8
Inflammation
Prognosis
Proliferation
TIL
TNBC
Journal
Journal of cancer research and clinical oncology
ISSN: 1432-1335
Titre abrégé: J Cancer Res Clin Oncol
Pays: Germany
ID NLM: 7902060
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
received:
23
08
2019
accepted:
19
09
2019
pubmed:
29
9
2019
medline:
23
11
2019
entrez:
29
9
2019
Statut:
ppublish
Résumé
Tumor inflammatory response was evaluated as a prognostic feature in triple-negative breast cancer (TNBC) and compared with the clinical prognosticators of breast cancer and selected biomarkers of cancer cell proliferation. TNBC patients (n = 179) with complete clinical data and up to 18-year follow-up were obtained from Auria biobank, Turku University Hospital, Turku, Finland. Tumor-infiltrating lymphocytes (TILs) and several subtypes of inflammatory cells detected with immunohistochemistry were evaluated in different tumor compartments in full tissue sections and tissue microarrays. Deficiency of stromal TILs and low number of CD8 TILs and CD8
Identifiants
pubmed: 31562550
doi: 10.1007/s00432-019-03036-5
pii: 10.1007/s00432-019-03036-5
pmc: PMC6861359
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3105-3114Références
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