Adverse transfusion reactions in transfused children.
Adolescent
Age Factors
Blood Component Transfusion
/ adverse effects
Blood Group Incompatibility
/ epidemiology
Child
Child, Preschool
Enterocolitis, Necrotizing
/ epidemiology
Erythrocytes
/ immunology
Forecasting
Graft vs Host Disease
/ epidemiology
Hemoglobinopathies
/ therapy
Humans
Infant
Infant, Newborn
Iron Overload
/ epidemiology
Practice Guidelines as Topic
Prevalence
Transfusion Reaction
/ epidemiology
Transfusion-Related Acute Lung Injury
/ epidemiology
Adverse transfusion reaction
Allergic reaction
Effet indésirable receveur
Paediatrics
Plaquette
Platelet
Pédiatrie
Receveur
Recipient
Réaction allergique
Transfusion
Journal
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
ISSN: 1953-8022
Titre abrégé: Transfus Clin Biol
Pays: France
ID NLM: 9423846
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
03
05
2019
accepted:
06
08
2019
pubmed:
30
9
2019
medline:
5
6
2020
entrez:
30
9
2019
Statut:
ppublish
Résumé
Transfusion in paediatrics requires specific guidelines, because child physiology and pathology differ significantly as compared to adults. Adverse transfusion reactions in transfused children also vary in type and frequency, but there is a better understanding of these reactions in adults than in children. However, for the most frequent adverse transfusion reactions, the overall prevalence is higher in children than in adults, with the exception of post-transfusion red blood cell alloimmunisation, which is lower, excluding patients with haemoglobinopathies. In several studies, allergic reactions were the most frequently reported adverse transfusion reaction in paediatrics, and the platelet concentrate the most frequently implicated blood product. Early diagnosis of certain adverse transfusion reactions such as haemosiderosis, is essential in order to initiate the best therapy and obtain a good clinical outcome. The prevention of adverse transfusion reactions in children is required, but needs further clinical studies in paediatrics. Lastly, changes in technology, policy and clinical practices will improve transfusion safety in children.
Identifiants
pubmed: 31563446
pii: S1246-7820(19)30435-5
doi: 10.1016/j.tracli.2019.08.002
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
329-335Informations de copyright
Copyright © 2019. Published by Elsevier Masson SAS.