questionsmedicales.fr
Maladies du système immunitaire
Réaction transfusionnelle
Réaction transfusionnelle : Questions médicales fréquentes
Diagnostic
5
Réaction transfusionnelle
Tests sanguins
Tests de compatibilité
Analyse sanguine
Symptômes
Transfusion sanguine
Historique médical
Antigènes
Symptômes
5
Douleur
Réaction transfusionnelle
Symptômes respiratoires
Réaction transfusionnelle
Éruption cutanée
Réaction transfusionnelle
Réaction allergique
Réaction transfusionnelle
Prévention
5
Prévention
Compatibilité sanguine
Consentement éclairé
Transfusion sanguine
Tests de compatibilité
Réaction transfusionnelle
Formation
Protocoles transfusionnels
Banques de sang
Tests préventifs
Traitements
5
Antihistaminiques
Corticostéroïdes
Surveillance
Complications
Fluides intraveineux
Pression artérielle
Médicaments immunosuppresseurs
Réaction sévère
Transfusions sanguines
Surveillance
Complications
5
Complications
Insuffisance rénale
Insuffisance rénale
Œdème
Choc
Réaction transfusionnelle
Infections
Transfusion sanguine
Gestion des complications
Prise en charge
Facteurs de risque
5
Facteurs de risque
Incompatibilité sanguine
Patients âgés
Complications
Femmes enceintes
Anticorps anti-Rh
Maladies auto-immunes
Réaction immunitaire
Transfusions multiples
Sensibilisation
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"@type": "Question",
"name": "Quand doit-on suspecter une réaction transfusionnelle ?",
"position": 4,
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{
"@type": "Question",
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"@type": "Question",
"name": "Quels sont les symptômes courants d'une réaction transfusionnelle ?",
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"position": 9,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Comment différencier une réaction allergique d'une transfusion ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
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{
"@type": "Question",
"name": "Comment prévenir les réactions transfusionnelles ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Assurer une compatibilité sanguine rigoureuse et un suivi des antécédents du patient."
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{
"@type": "Question",
"name": "Quel rôle joue le consentement éclairé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le consentement éclairé informe le patient des risques associés aux transfusions."
}
},
{
"@type": "Question",
"name": "Les tests de compatibilité sont-ils obligatoires ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils sont essentiels pour minimiser le risque de réactions transfusionnelles."
}
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{
"@type": "Question",
"name": "Comment former le personnel médical à la prévention ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des formations régulières sur les protocoles transfusionnels sont nécessaires."
}
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{
"@type": "Question",
"name": "Les banques de sang effectuent-elles des tests préventifs ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles réalisent des tests pour détecter des anticorps et des infections."
}
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{
"@type": "Question",
"name": "Quel est le traitement immédiat d'une réaction transfusionnelle ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Arrêter la transfusion et administrer des antihistaminiques ou des corticostéroïdes."
}
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{
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"name": "Faut-il surveiller le patient après une réaction ?",
"position": 17,
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{
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"name": "Les fluides intraveineux sont-ils nécessaires ?",
"position": 18,
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}
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{
"@type": "Question",
"name": "Quand utiliser des médicaments immunosuppresseurs ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "En cas de réactions sévères, des immunosuppresseurs peuvent être envisagés."
}
},
{
"@type": "Question",
"name": "Les transfusions futures nécessitent-elles des précautions ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
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}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles d'une réaction transfusionnelle ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent l'insuffisance rénale, le choc et les infections."
}
},
{
"@type": "Question",
"name": "Comment l'insuffisance rénale se manifeste-t-elle ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut se manifester par une diminution de la production d'urine et un œdème."
}
},
{
"@type": "Question",
"name": "Le choc peut-il être fatal ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le choc anaphylactique ou septique peut être mortel sans traitement rapide."
}
},
{
"@type": "Question",
"name": "Les infections sont-elles une préoccupation après une transfusion ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des infections virales ou bactériennes peuvent survenir après une transfusion."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications post-transfusionnelles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une prise en charge rapide et appropriée est cruciale pour limiter les séquelles."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de réactions transfusionnelles ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antécédents de transfusions, immunodépression et incompatibilité sanguine augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les patients âgés sont-ils plus à risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients âgés peuvent avoir un risque accru de complications transfusionnelles."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes sont-elles plus susceptibles ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent développer des anticorps anti-Rh, augmentant le risque lors de transfusions."
}
},
{
"@type": "Question",
"name": "Les patients ayant des maladies auto-immunes sont-ils à risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent avoir une réponse immunitaire exacerbée aux transfusions."
}
},
{
"@type": "Question",
"name": "Les transfusions multiples augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les transfusions répétées augmentent le risque de sensibilisation et de réactions."
}
}
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 10/04/2026
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Vigilance, Haemovigilance, établissement français du sang Auvergne Rhône-Alpes, site de Lyon Décines, 111, rue Elisée-Reclus CS 20617, 69153 Décines-Charpieu cedex, France.
Publications dans "Réaction transfusionnelle" :
4 publications dans cette catégorie
Affiliations :
Division of Blood Transfusion, Shinshu University Hospital, Matsumoto, Japan.
Centre for Advanced Cell Therapy, Shinshu University Hospital, Matsumoto, Japan.
Life Science Research Centre, Nagano Children's Hospital, Azumino, Japan.
Publications dans "Réaction transfusionnelle" :
3 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT.
Department of Pediatrics, Yale University School of Medicine, New Haven, CT.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Département des vigilances, hémovigilance, établissement français du sang Auvergne Rhône-Alpes, site de Lyon-Décines, 111, rue Élisée-Reclus, CS 20617, 69153 Décines-Charpieu cedex, France. Electronic address: pierre.moncharmont@efs.sante.fr.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, Nagano Children's Hospital, Azumino, Japan.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Life Science Research Centre, Nagano Children's Hospital, Azumino, Japan.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Clinical Department of Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia; University of Applied Health Sciences, Zagreb, Croatia.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT; Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, CT.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology and Surgery, Johns Hopkins Medical Institutions, Baltimore, MD.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT; Department of Pathology, Stony Brook School of Medicine.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Scientific Affairs, American Red Cross, Dedham, MA.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Wing-Kwai and Alice Lee-Tsing Chung Transfusion Service, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
Precision Diagnostics and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
University of Toronto Quality in Utilization, Education and Safety in Transfusion (QUEST) Research Program, Toronto, Ontario, Canada.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
INSERM U955 équipe 2, Institut Mondor de Recherche Biomédicale (IMRB), Créteil, France; Laboratoire d'excellence GR-Ex, F75739 Paris, France; Université Paris-Est-Créteil (UPEC), Créteil, France; Etablissement Français du Sang, Ile-de-France, Hôpital Henri-Mondor, Créteil, France. Electronic address: france.pirenne@efs.sante.fr.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Transfusion Medicine and Blood Bank, AIIMS Rishikesh, Rishikesh 249203, India.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Transfusion Medicine, London Health Sciences Centre, London, Ontario, Canada.
Division of Hematology, Department of Medicine, London Health Sciences Centre, London, Ontario, Canada.
Department of Pathology & Laboratory Medicine (PaLM), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Publications dans "Réaction transfusionnelle" :
2 publications dans cette catégorie
Affiliations :
Department of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China E-mail: deqingw@vip.sina.com.
Publications dans "Réaction transfusionnelle" :
ABO antigens are among the most immunogenic, but the haemolytic risks of ABO incompatibilities involving a donor with a weak ABO phenotype are little documented....
This retrospective case series assessed the incidence of acute haemolytic transfusion reaction (AHTR) among ABO-incompatible recipients of A...
Nine donors initially typed as Group B (N = 1) or O (N = 8) were subsequently found to display an A...
In this case series, no conclusive evidence of serious AHTR was found among ABO-incompatible recipients who were inadvertently transfused with A...
Blood transfusion is the infusion of whole blood or its components into the veins of the patient to improve tissue oxygenation and maintain hemostasis. Besides its clinical use, it can pose a risk of ...
The aim of this study was to assess blood transfusion complications, and associated factors among transfused adult patients at Tertiary care Hospital, Hyderabad, 2022....
An institution-based cross-sectional study design was conducted on a total of 182 patients from March 20 to June 15, 2022. Patients were enrolled in the study using consecutive sampling method. The so...
An acute transfusion reaction (ATR) was encountered in 12 (6.6%) patients. It was 4.13, 7.78 and 3.96 times more likely to occur among patients with a previous history of transfusion, abortion, and tr...
The incidence of acute transfusion reactions was high. During transfusion, clinicians should closely monitor patients who had history of transfusion, abortion, transfused old blood and more than 1 uni...
COVID-19 convalescent plasma (CCP) is an important therapeutic option for outpatients at high risk of hospitalization from SARS-CoV-2 infection. We assessed the safety of outpatient CCP transfusions a...
We analyzed data pertaining to transfusion-related reactions from two randomized controlled trials in the U.S. that evaluated the efficacy of CCP versus control plasma in various ambulatory settings. ...
The combined study reported 79/1351 (5.9%) adverse events during the transfusion visit, with the majority 62/1351 (4.6%) characterized by mild, allergic-type findings of urticaria, and/or pruritus con...
Outpatient plasma administration was safely performed for nearly 1400 participants. CCP is a safe therapeutic option for outpatients at risk of hospitalization from COVID-19....
Blood transfusion is a life-saving procedure widely used in healthcare. However, complications such as transfusion reactions may occur. Knowledge of these reactions is essential for patient safety. Nu...
The transfusion of blood products is a life-saving clinical practice in patients with bleeding, hemoglobinopathy, and cancer. It was aimed herein to analyze the frequency and types of blood component-...
This retrospective study was conducted at a tertiary care academic pediatric hospital....
During the study period, 30,811 transfusions were administered to 25,448 patients. There were 103 ATRs detected in 81 patients (0.33%; 3.34 reactions per 1000 transfusions, mean age 8.3 ± 5.98 years, ...
Within our hospital, pediatric hematology-oncology wards and the stem cell transplantation unit had the most frequent ATR reports; therefore, when transfusions are carried out, increased attention sho...
Acute hemolytic transfusion reaction (AHTR) due to ABO-incompatible erythrocyte concentrate (EC) is one of the most catastrophic complications of transfusion. Since the hemolysis is intravascular; hem...
Treatment of AHTR is mostly supportive measures. Today there are no clear suggestions about plasma exchange (PE) in these patients....
Here we report our experience with six patients diagnosed with AHTR due to ABO-incompatible EC transfusion....
We performed PE in 5 of these patients. Although all of our patients were geriatric and most of them had significant comorbidities four out of five patients recovered without an incident....
Although PE is considered a last-chance treatment when other measures fail in the literature, our experience above indicates that it must be evaluated in every patient with AHTR early in the course. I...
Octaplas is a solvent/detergent (S/D)-treated pooled human plasma indicated for the treatment of thrombotic thrombocytopenic purpura (TTP) as well as multiple coagulation factor deficiency in patients...
A single-center retrospective review of patient records was performed from January 2018 through July 2022 for patients who received S/D treated plasma (Octaplas™; Octapharma)....
A total of 1415 units of S/D-treated plasma were transfused to nine patients at our institution. Patient ages ranged from 13 months to 25 years old. The reason to initiate transfusion with S/D treated...
We have successfully utilized S/D treated plasma over the last 4.5 years for pediatric, adolescent, and young adult patients who otherwise would have suffered ATR due to necessary TPE or PT. S/D treat...
We present a never-transfused girl with thalassemia intermedia who was admitted for febrile aplastic crisis due to human parvovirus B19. After a first transfusion of packed red blood cells, she develo...
Sc1 is a high-prevalence blood group antigen that is part of the Scianna blood group system. The clinical significance of Scianna antibodies is not well understood because of their rarity; there are o...
Blood transfusion is an important mode of infectious disease transmission in low- and middle-income countries (LMICs). This study describes a model to determine the prevalence of transfusion-transmitt...
A five-step model was developed to determine the TTI-related burden of disease measured by disability-adjusted life years (DALYs). Uganda was selected as the study country....
Approximately 298,266 units of blood were transfused in Uganda in 2019, yielding an estimated TTI incidence of 6,858 new TTIs (2.3% of transfused units) and prevalence of 19,141 TTIs (6.4% of transfus...
The incidence and prevalence of TTIs and the associated burden of disease can be calculated on a local and national level. The model can be applied by health ministries to estimate the impact of TTIs ...