Deriving literature-based benchmarks for pediatric appendectomy and cholecystectomy complications from national databases in high-income countries: A systematic review and meta-analysis.


Journal

Journal of pediatric surgery
ISSN: 1531-5037
Titre abrégé: J Pediatr Surg
Pays: United States
ID NLM: 0052631

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 15 08 2019
accepted: 24 08 2019
pubmed: 3 10 2019
medline: 26 3 2020
entrez: 3 10 2019
Statut: ppublish

Résumé

Health systems must identify preventable adverse outcomes to improve surgical safety. We conducted a systematic review to determine national rates of postoperative complications associated with two common pediatric surgery operations in High-Income Countries (HICs). National database studies of complication rates associated with pediatric appendectomies and cholecystectomies (2000-2016) in Canada, the US, and the UK were included. Outcomes included mortality, length of hospital stay (LOS), and other surgical complications. Outcome data were extracted and comparisons made between countries and databases. Thirty-three papers met inclusion criteria (1 Canadian, 1 UK, and 4 US Databases). Mean LOS was 3.00 (±1.42) days and 3.44 (±1.55) days for appendectomy and cholecystectomy, respectively. Mortality was 0.06% after appendectomy and 0.24% after cholecystectomy. Readmission and reoperation rates were 6.79% and 0.32% for appendectomy, and 1.37% and 0.71% for cholecystectomy. For appendectomies, LOS was shorter in Canadian and UK studies compared to US studies, and mortality and readmission rates were lower (OR 0.46 95%CI 0.23 to 0.93, OR 3.63 to 3.77 95%CI) in UK studies compared to US studies. Outcomes after pediatric appendectomy and cholecystectomy are good but vary between HICs. Understanding national outcomes and intercountry differences is essential in developing health system approaches to pediatric surgical safety. II.

Sections du résumé

BACKGROUND BACKGROUND
Health systems must identify preventable adverse outcomes to improve surgical safety. We conducted a systematic review to determine national rates of postoperative complications associated with two common pediatric surgery operations in High-Income Countries (HICs).
METHODS METHODS
National database studies of complication rates associated with pediatric appendectomies and cholecystectomies (2000-2016) in Canada, the US, and the UK were included. Outcomes included mortality, length of hospital stay (LOS), and other surgical complications. Outcome data were extracted and comparisons made between countries and databases.
RESULTS RESULTS
Thirty-three papers met inclusion criteria (1 Canadian, 1 UK, and 4 US Databases). Mean LOS was 3.00 (±1.42) days and 3.44 (±1.55) days for appendectomy and cholecystectomy, respectively. Mortality was 0.06% after appendectomy and 0.24% after cholecystectomy. Readmission and reoperation rates were 6.79% and 0.32% for appendectomy, and 1.37% and 0.71% for cholecystectomy. For appendectomies, LOS was shorter in Canadian and UK studies compared to US studies, and mortality and readmission rates were lower (OR 0.46 95%CI 0.23 to 0.93, OR 3.63 to 3.77 95%CI) in UK studies compared to US studies.
CONCLUSIONS CONCLUSIONS
Outcomes after pediatric appendectomy and cholecystectomy are good but vary between HICs. Understanding national outcomes and intercountry differences is essential in developing health system approaches to pediatric surgical safety.
LEVEL OF EVIDENCE METHODS
II.

Identifiants

pubmed: 31575414
pii: S0022-3468(19)30573-1
doi: 10.1016/j.jpedsurg.2019.08.033
pii:
doi:

Types de publication

Comparative Study Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2528-2538

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Oluwatomilayo O Daodu (OO)

Section of Pediatric Surgery, Alberta Children's Hospital, Calgary, Alberta, Canada.

Nathan Zondervan (N)

Department of Surgery, Cumming School of Medicine, University of Calgary, Foothills Medical Centre Calgary, Alberta, Canada.

Denisa Urban (D)

Section of Pediatric Surgery, Alberta Children's Hospital, Calgary, Alberta, Canada.

Ali MacRobie (A)

Section of Pediatric Surgery, Alberta Children's Hospital, Calgary, Alberta, Canada.

Mary Brindle (M)

Section of Pediatric Surgery, Alberta Children's Hospital, Calgary, Alberta, Canada; Department of Surgery, Cumming School of Medicine, University of Calgary, Foothills Medical Centre Calgary, Alberta, Canada. Electronic address: MaryEBrindle@gmail.com.

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