Biological transformation of fexofenadine and sitagliptin by carrier-attached biomass and suspended sludge from a hybrid moving bed biofilm reactor.
Biotransformation
Fexofenadine
Moving bed biofilm reactor
Sitagliptin
Transformation products
Journal
Water research
ISSN: 1879-2448
Titre abrégé: Water Res
Pays: England
ID NLM: 0105072
Informations de publication
Date de publication:
15 Dec 2019
15 Dec 2019
Historique:
received:
24
05
2019
revised:
09
08
2019
accepted:
30
08
2019
pubmed:
4
10
2019
medline:
4
12
2019
entrez:
4
10
2019
Statut:
ppublish
Résumé
Laboratory-scale experiments were conducted to investigate the (bio)transformation of the antidiabetic sitagliptin (STG) and the antihistamine fexofenadine (FXF) during wastewater treatment. As inoculum either attached-growth on carriers or suspended sludge from a hybrid moving bed biofilm reactor (HMBBR) was used. Both target compounds were incubated in degradation experiments and quantified via LC-MS/MS for degradation kinetics. Furthermore transformation products (TPs) were analyzed via high resolution mass spectrometry (HRMS). Structural elucidation of the TPs was based on the high resolution molecular ion mass to propose a molecular formula and on MS
Identifiants
pubmed: 31581038
pii: S0043-1354(19)30808-5
doi: 10.1016/j.watres.2019.115034
pii:
doi:
Substances chimiques
Sewage
0
Terfenadine
7BA5G9Y06Q
fexofenadine
E6582LOH6V
Sitagliptin Phosphate
TS63EW8X6F
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
115034Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.