Perioperative and long-term outcomes of laparoscopic liver resections for non-colorectal liver metastases.
Adult
Aged
Aged, 80 and over
Colorectal Neoplasms
Female
Follow-Up Studies
France
/ epidemiology
Hepatectomy
/ methods
Humans
Laparoscopy
/ methods
Liver Neoplasms
/ mortality
Male
Margins of Excision
Middle Aged
Neoplasm Metastasis
Perioperative Period
Retrospective Studies
Survival Rate
/ trends
Time Factors
Young Adult
Laparoscopic liver resection
Non-colorectal liver metastases
Overall
Postoperative outcomes
Recurrence-free survivals
Journal
Surgical endoscopy
ISSN: 1432-2218
Titre abrégé: Surg Endosc
Pays: Germany
ID NLM: 8806653
Informations de publication
Date de publication:
09 2020
09 2020
Historique:
received:
27
03
2019
accepted:
24
09
2019
pubmed:
6
10
2019
medline:
25
5
2021
entrez:
6
10
2019
Statut:
ppublish
Résumé
Liver is a common metastatic site not only of colorectal but of non-colorectal neoplasms, as well. However, resection of non-colorectal liver metastases (NCRLMs) remains controversial. The aim of this retrospective study was to analyze the short- and long-term outcomes of patients undergoing laparoscopic liver resection (LLR) for NCRLMs. From a prospectively maintained database between 2000 and 2018, patients undergoing LLR for colorectal liver metastases (CRLMs) and NCRLMs were selected. Clinicopathologic, operative, short- and long-term outcome data were collected, analyzed, and compared among patients with CRLMs and NCRLMs. The primary tumor was colorectal in 354 (82.1%), neuroendocrine in 21 (4.9%), and non-colorectal, non-neuroendocrine in the remaining 56 (13%) patients. Major postoperative morbidities were 12.7%, 19%, and 3.6%, respectively (p = 0.001), whereas the mortality was 0.6% for patients with CRLMs and zero for patients with NCRLMs. The rate of R LLR is safe and feasible in the context of a multimodal management where an aggressive surgical approach, necessitating even complex procedures for bilobar multifocal metastases and repeat hepatectomy for recurrences, is the mainstay and may be of benefit in the long-term survival, in selected patients with NCRNNELMs.
Sections du résumé
BACKGROUND
Liver is a common metastatic site not only of colorectal but of non-colorectal neoplasms, as well. However, resection of non-colorectal liver metastases (NCRLMs) remains controversial. The aim of this retrospective study was to analyze the short- and long-term outcomes of patients undergoing laparoscopic liver resection (LLR) for NCRLMs.
METHODS
From a prospectively maintained database between 2000 and 2018, patients undergoing LLR for colorectal liver metastases (CRLMs) and NCRLMs were selected. Clinicopathologic, operative, short- and long-term outcome data were collected, analyzed, and compared among patients with CRLMs and NCRLMs.
RESULTS
The primary tumor was colorectal in 354 (82.1%), neuroendocrine in 21 (4.9%), and non-colorectal, non-neuroendocrine in the remaining 56 (13%) patients. Major postoperative morbidities were 12.7%, 19%, and 3.6%, respectively (p = 0.001), whereas the mortality was 0.6% for patients with CRLMs and zero for patients with NCRLMs. The rate of R
CONCLUSION
LLR is safe and feasible in the context of a multimodal management where an aggressive surgical approach, necessitating even complex procedures for bilobar multifocal metastases and repeat hepatectomy for recurrences, is the mainstay and may be of benefit in the long-term survival, in selected patients with NCRNNELMs.
Identifiants
pubmed: 31586246
doi: 10.1007/s00464-019-07148-4
pii: 10.1007/s00464-019-07148-4
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM