Unyvero ITI
Diagnosis
PCR
Prosthetic joint infection
Journal
Musculoskeletal surgery
ISSN: 2035-5114
Titre abrégé: Musculoskelet Surg
Pays: Italy
ID NLM: 101498346
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
11
09
2019
accepted:
01
10
2019
pubmed:
9
10
2019
medline:
29
10
2021
entrez:
10
10
2019
Statut:
ppublish
Résumé
The Unyvero molecular assay was tested for the clinical resolution of discordant results, evaluating its role in prosthetic joint infection diagnosis. Multiplex PCR was performed on 45 samples from prosthesis treatment (either sonication or dithiothreitol). Analytical performance was compared to that of biofilm culture using Musculoskeletal Infection Society criteria as gold standard. Unyvero and biofilm culture showed similar agreement rates compared to the gold standard (34/43 and 32/43, respectively). Both methods showed six additional identifications compatible with true infection; five positive results from biofilm culture were deemed contaminations. The Unyvero system showed good performances and a significantly shorter turnaround time compared to cultural methods, presenting an added value to PJI diagnosis even when performed following a composite approach.
Identifiants
pubmed: 31595427
doi: 10.1007/s12306-019-00626-x
pii: 10.1007/s12306-019-00626-x
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
39-42Références
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