Sensitivity and Specificity of the Modified Epworth Sleepiness Scale in Children With Craniopharyngioma.
Adolescent
Adult
Child
Craniopharyngioma
/ complications
Disorders of Excessive Somnolence
/ complications
Female
Humans
Male
Pituitary Neoplasms
/ complications
Polysomnography
/ statistics & numerical data
Reproducibility of Results
Sensitivity and Specificity
Sleep Latency
/ physiology
Sleepiness
Young Adult
CNS tumor
Modified Epworth Sleepiness Scale
Multiple Sleep Latency Test
craniopharyngioma
excessive daytime sleepiness (EDS)
pediatrics
Journal
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977
Informations de publication
Date de publication:
15 10 2019
15 10 2019
Historique:
entrez:
10
10
2019
pubmed:
10
10
2019
medline:
11
11
2020
Statut:
ppublish
Résumé
Children with craniopharyngioma are at risk for excessive daytime sleepiness (EDS). Multiple Sleep Latency Testing (MSLT) is the gold standard for objective evaluation of EDS; however, it is time and resource intensive. We compared the reliability, sensitivity, and specificity of the modified Epworth Sleepiness Scale (M-ESS) and MSLT in monitoring EDS in children with craniopharyngioma. Seventy patients (ages 6 to 20 years) with craniopharyngioma completed the M-ESS and were evaluated by polysomnography and MSLT. Evaluations were made after surgery, if performed, and before proton therapy. MSLT revealed that 66 participants (81.8%) had EDS, as defined by a mean sleep latency (MSL) < 10 minutes, with only 28.8% reporting EDS on the M-ESS by using a cutoff score of 10. The M-ESS demonstrated adequate internal consistency and specificity (91.7%) but poor sensitivity (33.3%) with the established cutoff score of 10. A cutoff score of 6 improved the sensitivity to 64.8% but decreased the specificity to 66.7%. Patients with craniopharyngioma are at high risk for EDS, as documented objectively on the MSLT, but they frequently do not recognize or accurately report their sleepiness. Future sleep studies should investigate whether specific items or alternative self- and parent-reported measures of sleepiness may have greater clinical utility in monitoring sleepiness in this population.
Identifiants
pubmed: 31596214
doi: 10.5664/jcsm.7982
pmc: PMC6778340
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1487-1493Informations de copyright
© 2019 American Academy of Sleep Medicine.
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