Metabolic profiling of seminal plasma from teratozoospermia patients.

Biomarkers / metabolism Case-Control Studies Humans Infertility, Male / diagnosis Magnetic Resonance Spectroscopy Male Metabolome Metabolomics Proton Magnetic Resonance Spectroscopy Semen / metabolism Teratozoospermia / diagnosis
Human seminal plasma Male infertility Metabolomics NMR Teratozoospermia

Journal

Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336

Informations de publication

Date de publication:
30 Jan 2020
Historique:
received: 28 07 2019
revised: 28 09 2019
accepted: 30 09 2019
pubmed: 13 10 2019
medline: 3 6 2020
entrez: 13 10 2019
Statut: ppublish

Résumé

Teratozoospermia is one of conditions that can cause male infertility. The mechanism of teratozoospermia remains unclear. The knowledge of the metabolites in human seminal plasma (HSP) is meaningful for the pathological study of teratozoospermia. Analysis of changed metabolites in HSP can help understand the cellular mechanism, find the novel biomarkers and subsequently design a diagnosis test. In this study, the analysis of samples performed by proton nuclear magnetic resonance spectroscopy (

Identifiants

DOI: 10.1016/j.jpba.2019.112903 PMID: 31605879
pubmed: 31605879
pii: S0731-7085(19)31869-2
doi: 10.1016/j.jpba.2019.112903
pii:
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112903

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Bahareh Mehrparvar (B)

Reproductive Immunology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran; Integrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran.

Saeed Chashmniam (S)

Department of chemistry, Sharif University of Technology, Tehran, Iran.

Fatemeh Nobakht (F)

Chemical Injuries Research Center, Systems Biology and Poisoning Institute, Baghiyatallah University of Medical Sciences, Tehran, Iran.

Mehdi Amini (M)

Reproductive Immunology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Amin Javidi (A)

Department of Molecular and Cellular Science, Faculty of Advanced Sciences and Technology, Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran; Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran; Cancer Alternative and Complementary Medicine Department, Breast Cancer Research Center, ACECR, Tehran, Iran.

Arash Minai-Tehrani (A)

Nanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.

Babak Arjmand (B)

Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism Molecular Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Kambiz Gilany (K)

Reproductive Immunology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran; Integrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran. Electronic address: k.gilany@ari.ir.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études cas-témoins › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Maladies urogénitales › Maladies urogénitales de l'homme › Maladies de l'appareil génital mâle › Infertilité masculine › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Métabolisme › Métabolome › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Métabolomique › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie par résonance magnétique du proton › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Liquides et sécrétions biologiques › Sécrétions corporelles › Sperme › Metabolic profiling of seminal plasma from...
questionsmedicales.fr › Maladies urogénitales › Maladies urogénitales de l'homme › Maladies de l'appareil génital mâle › Infertilité masculine › Tératozoospermie › Metabolic profiling of seminal plasma from...