The Impact of Ethnicity on Craniosynostosis in the United States.


Journal

The Journal of craniofacial surgery
ISSN: 1536-3732
Titre abrégé: J Craniofac Surg
Pays: United States
ID NLM: 9010410

Informations de publication

Date de publication:
Historique:
pubmed: 15 10 2019
medline: 28 1 2020
entrez: 15 10 2019
Statut: ppublish

Résumé

While many studies have examined potential risk factors for nonsyndromic craniosynostosis, there have been no publications to date investigating the role of ethnicity in the United States. The current study was undertaken as the first multi-center investigation to examine the relationship between ethnicity and nonsyndromic craniosynostosis, looking at both overall prevalence as well as potential correlation between ethnicity and pattern of affected suture site. A chart review of patients diagnosed with nonsyndromic craniosynostosis treated at four major children's hospitals was performed to obtain ethnicity data. Analysis was preformed based on ethnic group as well as suture site affected. To account for potentialOne regional selection bias, the KID database (1997-2012) was utilized to identify all cases of craniosynostosis on a national level. This data was analyzed against birth rates by ethnicity obtained from CDC WONDER natality database.Amongst the 2112 cases of nonsyndromic craniosynostosis at all institutions, Caucasians and African Americans were consistently the predominant ethnic groups. There was a statistically significant difference in the distribution of affected suture type with African Americans more likely to present with unicoronal synostosis and Caucasians more likely to present with metopic synostosis (P = 0.005). The national data revealed that there were more cases of craniosynostosis in Caucasians and fewer in African Americans than expected when compared to population birth rates. Our findings demonstrate that the Caucasian race is associated with increased rates of synostosis.

Identifiants

pubmed: 31609944
doi: 10.1097/SCS.0000000000006009
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2526-2529

Auteurs

Gina N Sacks (GN)

Division of Plastic and Reconstructive Surgery, Washington University, St. Louis Children's Hospital, St. Louis, MO.

Gary B Skolnick (GB)

Division of Plastic and Reconstructive Surgery, Washington University, St. Louis Children's Hospital, St. Louis, MO.

Ali Trachtenberg (A)

Section of Plastic Surgery, University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, MI.

Sybill D Naidoo (SD)

Division of Plastic and Reconstructive Surgery, Washington University, St. Louis Children's Hospital, St. Louis, MO.

Joseph Lopez (J)

Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.

Albert K Oh (AK)

Division of Plastic and Reconstructive Surgery, Children's National Medical Center, Washington DC.

Jerry W Chao (JW)

Division of Plastic and Reconstructive Surgery, Children's National Medical Center, Washington DC.

Amir Dorafshar (A)

Department of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD.

Christian J Vercler (CJ)

Section of Plastic Surgery, University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, MI.

Steven R Buchman (SR)

Section of Plastic Surgery, University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, MI.

Kamlesh Patel (K)

Division of Plastic and Reconstructive Surgery, Washington University, St. Louis Children's Hospital, St. Louis, MO.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH