Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study.


Journal

Journal of autism and developmental disorders
ISSN: 1573-3432
Titre abrégé: J Autism Dev Disord
Pays: United States
ID NLM: 7904301

Informations de publication

Date de publication:
Jan 2020
Historique:
pubmed: 18 10 2019
medline: 4 4 2020
entrez: 18 10 2019
Statut: ppublish

Résumé

Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored.

Identifiants

pubmed: 31621020
doi: 10.1007/s10803-019-04234-3
pii: 10.1007/s10803-019-04234-3
pmc: PMC6946757
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

308-318

Subventions

Organisme : Baily Thomas Charitable Fund
ID : 3747-6849
Organisme : Vetenskapsrådet
ID : 2017-010006
Organisme : National Institute for Health Research
ID : BRC-1215-2011
Organisme : National Institute for Health Research
ID : ACF-2016-25-503

Références

J Am Acad Child Adolesc Psychiatry. 2012 May;51(5):467-476.e6
pubmed: 22525953
Child Abuse Negl. 2015 Jul;45:135-42
pubmed: 25957197
Int Rev Psychiatry. 2018 Feb;30(1):40-61
pubmed: 29683351
J Autism Dev Disord. 2016 Jan;46(1):74-82
pubmed: 26210519
J Ment Health Res Intellect Disabil. 2008;1(4):238-253
pubmed: 24009649
PLoS One. 2012;7(7):e41280
pubmed: 22911770
Res Dev Disabil. 2010 Nov-Dec;31(6):1669-77
pubmed: 20493660
Psychol Med. 2015 Feb;45(3):601-13
pubmed: 25108395
PLoS One. 2015 Nov 11;10(11):e0141703
pubmed: 26558765
BMJ Open. 2015 Jun 22;5(6):e007520
pubmed: 26100027
Autism Res. 2008 Jun;1(3):193-7
pubmed: 19360666
Am J Psychiatry. 2002 Apr;159(4):620-9
pubmed: 11925301
Eur J Public Health. 2006 Dec;16(6):633-9
pubmed: 16641161
Br J Psychiatry. 2005 Jun;186:525-8
pubmed: 15928364
Int J Neuropsychopharmacol. 2001 Jun;4(2):119-25
pubmed: 11466160
Br J Psychiatry. 2016 Dec;209(6):498-503
pubmed: 27388569
JAMA Psychiatry. 2016 Jun 1;73(6):622-9
pubmed: 27145529
Trends Cogn Sci. 2011 Sep;15(9):409-16
pubmed: 21855394
JAMA Netw Open. 2019 Mar 1;2(3):e190154
pubmed: 30821823
Br J Psychiatry. 2006 Oct;189:361-6
pubmed: 17012660
Curr Opin Psychiatry. 2015 Mar;28(2):83-90
pubmed: 25602249
JAMA Netw Open. 2018 Aug 3;1(4):e181465
pubmed: 30646131
Pediatr Res. 2009 Jun;65(6):591-8
pubmed: 19218885
J Abnorm Child Psychol. 2013 Jan;41(1):165-76
pubmed: 22850932
J Intellect Disabil. 2007 Dec;11(4):359-70
pubmed: 18029412
J Psychopharmacol. 2018 Jan;32(1):3-29
pubmed: 29237331
Autism. 2016 Jul;20(5):623-7
pubmed: 26471427
Lancet. 2014 Mar 8;383(9920):896-910
pubmed: 24074734
J Autism Dev Disord. 2003 Oct;33(5):489-507
pubmed: 14594329
Autism. 2008 Jul;12(4):373-90
pubmed: 18579645
Clin Child Fam Psychol Rev. 2011 Sep;14(3):302-17
pubmed: 21735077
J Autism Dev Disord. 2015 Nov;45(11):3475-86
pubmed: 25711547
Am J Psychiatry. 2012 Mar;169(3):292-9
pubmed: 22193531
J Abnorm Child Psychol. 2008 Jan;36(1):117-28
pubmed: 17674186
Arch Gen Psychiatry. 1996 Nov;53(11):1001-8
pubmed: 8911223
J Autism Dev Disord. 2015 Jun;45(6):1766-73
pubmed: 25475364
J Autism Dev Disord. 2014 Dec;44(12):3063-71
pubmed: 24958436
Acta Psychiatr Scand. 2009 Nov;120(5):386-91
pubmed: 19807720
J Autism Dev Disord. 2014 Nov;44(11):2851-61
pubmed: 24902932
J Child Psychol Psychiatry. 2016 Jun;57(6):759-69
pubmed: 26714925
JAMA Pediatr. 2014 Aug;168(8):721-8
pubmed: 24911948
BMC Psychiatry. 2009 Jun 10;9:35
pubmed: 19515234
Psychol Med. 1998 Mar;28(2):385-95
pubmed: 9572095
Autism. 2015 Oct;19(7):814-23
pubmed: 25911091
Psychiatry Res. 2013 May 30;207(3):203-11
pubmed: 23391634
BMC Public Health. 2011 Jun 09;11:450
pubmed: 21658213
J Child Adolesc Psychopharmacol. 2005 Jun;15(3):477-96
pubmed: 16092912
J Autism Dev Disord. 2016 Jun;46(6):1916-1930
pubmed: 26861713
Clin Psychol Rev. 2009 Apr;29(3):216-29
pubmed: 19223098

Auteurs

Victoria Nimmo-Smith (V)

Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK. victoria.nimmo-smith@bristol.ac.uk.
Avon & Wiltshire Partnership NHS Mental Health Trust, Bristol, UK. victoria.nimmo-smith@bristol.ac.uk.

Hein Heuvelman (H)

Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

Christina Dalman (C)

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Centre for Epidemiology and Community Medicine, Stockholm County Council, Stockholm, Sweden.

Michael Lundberg (M)

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Centre for Epidemiology and Community Medicine, Stockholm County Council, Stockholm, Sweden.

Selma Idring (S)

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Centre for Epidemiology and Community Medicine, Stockholm County Council, Stockholm, Sweden.

Peter Carpenter (P)

Avon & Wiltshire Partnership NHS Mental Health Trust, Bristol, UK.

Cecilia Magnusson (C)

Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.

Dheeraj Rai (D)

Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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