Update on treatments for erosive vulvovaginal lichen planus.
Administration, Oral
Administration, Topical
Algorithms
Antibodies, Monoclonal
/ administration & dosage
Calcineurin Inhibitors
/ administration & dosage
Dermatologic Agents
/ administration & dosage
Drug Therapy, Combination
Female
Glucocorticoids
/ administration & dosage
Gynecologic Surgical Procedures
Humans
Lichen Planus
/ drug therapy
Methotrexate
/ administration & dosage
Mycophenolic Acid
/ administration & dosage
Photochemotherapy
Tacrolimus
/ administration & dosage
Ultrasonic Therapy
Vulvovaginitis
/ drug therapy
Journal
International journal of dermatology
ISSN: 1365-4632
Titre abrégé: Int J Dermatol
Pays: England
ID NLM: 0243704
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
24
05
2019
revised:
02
08
2019
accepted:
20
09
2019
pubmed:
22
10
2019
medline:
29
9
2020
entrez:
22
10
2019
Statut:
ppublish
Résumé
Vulvovaginal lichen planus (VVLP) is a debilitating disease that causes significant pain and psychological distress. Management is made difficult by the chronic course of the disease and its resistance to treatment. While topical steroids have been accepted as the first-line treatment, they fail to achieve symptomatic control in approximately 40% of patients. Second-line therapies include other topical treatments such as calcineurin inhibitors, systemic therapies including oral steroids, methotrexate, mycophenolate mofetil, biologics, and tacrolimus, and procedural options including surgery and dilation, photodynamic therapy, and ultrasound. This review provides an overview of the current treatments and explores the level of evidence supporting each of them.
Substances chimiques
Antibodies, Monoclonal
0
Calcineurin Inhibitors
0
Dermatologic Agents
0
Glucocorticoids
0
Mycophenolic Acid
HU9DX48N0T
Tacrolimus
WM0HAQ4WNM
Methotrexate
YL5FZ2Y5U1
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
297-302Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2019 The International Society of Dermatology.
Références
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