Ralstonia mannitolilytica sepsis: a case report.
16S rRNA
Case report
Nonfermenting gram-negative rods
Ralstonia mannitolilytica
Sepsis
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
26 Oct 2019
26 Oct 2019
Historique:
received:
22
04
2019
accepted:
16
08
2019
entrez:
27
10
2019
pubmed:
28
10
2019
medline:
6
2
2020
Statut:
epublish
Résumé
Ralstonia mannitolilytica is an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections. Reports on this pathogen are limited, however, especially on the African continent. A 2-year-old Akan child was presented to a hospital in the northeastern part of Ghana with a 1-week history of fever and chills. We identified Ralstonia mannitolilytica in her blood culture using both conventional and 16S ribosomal deoxyribonucleic acid (rDNA) techniques. The patient's condition improved clinically upon treatment with cefuroxime. Our report highlights the potential of Ralstonia mannitolilytica to cause sepsis and thus emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
Sections du résumé
BACKGROUND
BACKGROUND
Ralstonia mannitolilytica is an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections. Reports on this pathogen are limited, however, especially on the African continent.
CASE PRESENTATION
METHODS
A 2-year-old Akan child was presented to a hospital in the northeastern part of Ghana with a 1-week history of fever and chills. We identified Ralstonia mannitolilytica in her blood culture using both conventional and 16S ribosomal deoxyribonucleic acid (rDNA) techniques. The patient's condition improved clinically upon treatment with cefuroxime.
CONCLUSION
CONCLUSIONS
Our report highlights the potential of Ralstonia mannitolilytica to cause sepsis and thus emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
Identifiants
pubmed: 31653273
doi: 10.1186/s13256-019-2235-0
pii: 10.1186/s13256-019-2235-0
pmc: PMC6815052
doi:
Substances chimiques
Anti-Bacterial Agents
0
RNA, Ribosomal, 16S
0
Cefuroxime
O1R9FJ93ED
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
318Références
Jundishapur J Microbiol. 2016 Jul 02;9(7):e34373
pubmed: 27679705
Indian J Med Microbiol. 2003 Oct-Dec;21(4):284-6
pubmed: 17643046
J Clin Microbiol. 2001 Dec;39(12):4588-90
pubmed: 11724893
Antimicrob Agents Chemother. 2004 Nov;48(11):4217-25
pubmed: 15504844
Pediatrics. 2007 Jun;119(6):1061-8
pubmed: 17545371
J Med Case Rep. 2017 Mar 23;11(1):77
pubmed: 28330494
Int J Syst Evol Microbiol. 2001 Mar;51(Pt 2):547-58
pubmed: 11321101
Antimicrob Resist Infect Control. 2017 Feb 7;6:20
pubmed: 28191308
J Clin Microbiol. 2005 Jul;43(7):3463-6
pubmed: 16000479