Expressions of natural cytotoxicity receptor, NKG2D and NKG2D ligands in endometriosis.
Adult
CD56 Antigen
/ immunology
Endometriosis
/ immunology
Female
GPI-Linked Proteins
/ immunology
Gene Expression Regulation
/ immunology
Humans
Killer Cells, Natural
/ immunology
Middle Aged
NK Cell Lectin-Like Receptor Subfamily K
/ immunology
Natural Cytotoxicity Triggering Receptor 1
/ immunology
Natural Cytotoxicity Triggering Receptor 3
/ immunology
Receptors, IgG
/ immunology
NKG2D
NKG2D ligands
Natural cytotoxicity receptors
Ovarian endometriosis
Journal
Journal of reproductive immunology
ISSN: 1872-7603
Titre abrégé: J Reprod Immunol
Pays: Ireland
ID NLM: 8001906
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
06
02
2019
revised:
04
08
2019
accepted:
17
09
2019
pubmed:
28
10
2019
medline:
29
5
2020
entrez:
27
10
2019
Statut:
ppublish
Résumé
Pathogenesis of endometriosis is still unknown, and the relationship between NK cell activating receptors and endometriosis remains to be explored. We investigated the expression of NCRs and NKG2D in NK cells in peripheral blood (PB) and peritoneal fluid (PF) as well as expression of NKG2D ligands in endometrial cells, and illuminated their relationship with ovarian endometriosis. 20 patients with ovarian endometriosis and 13 subjects for control group were recruited. Flow cytometry was used for examining expressions of NCRs and NKG2D on NK cells. In PF with endometriosis, the expressions of NKp30 (P = 0. 006) and NKG2D (P = 0. 010) on CD56
Identifiants
pubmed: 31655348
pii: S0165-0378(19)30008-7
doi: 10.1016/j.jri.2019.102615
pii:
doi:
Substances chimiques
CD56 Antigen
0
FCGR3B protein, human
0
GPI-Linked Proteins
0
KLRK1 protein, human
0
NCAM1 protein, human
0
NCR1 protein, human
0
NCR3 protein, human
0
NK Cell Lectin-Like Receptor Subfamily K
0
Natural Cytotoxicity Triggering Receptor 1
0
Natural Cytotoxicity Triggering Receptor 3
0
Receptors, IgG
0
Types de publication
Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102615Informations de copyright
Copyright © 2019 The Author. Published by Elsevier B.V. All rights reserved.