Downregulation of MHC Class II by Ubiquitination Is Required for the Migration of CD206
Animals
Cell Movement
Dendritic Cells
/ metabolism
Down-Regulation
Histocompatibility Antigens Class II
/ metabolism
Lectins, C-Type
/ metabolism
Lymph Nodes
/ metabolism
Mannose Receptor
Mannose-Binding Lectins
/ metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Receptors, Cell Surface
/ metabolism
Skin
/ metabolism
Ubiquitination
Journal
Journal of immunology (Baltimore, Md. : 1950)
ISSN: 1550-6606
Titre abrégé: J Immunol
Pays: United States
ID NLM: 2985117R
Informations de publication
Date de publication:
01 12 2019
01 12 2019
Historique:
received:
23
05
2019
accepted:
20
09
2019
pubmed:
30
10
2019
medline:
28
5
2020
entrez:
30
10
2019
Statut:
ppublish
Résumé
Dendritic cells (DCs) are critical players in skin homeostasis. A subset of mannose receptor (CD206)-expressing monocyte-derived DCs was found in skin, and their migratory counterpart is present in skin-draining lymph nodes (sdLNs). Skin CD206
Identifiants
pubmed: 31659013
pii: jimmunol.1900593
doi: 10.4049/jimmunol.1900593
doi:
Substances chimiques
Histocompatibility Antigens Class II
0
Lectins, C-Type
0
Mannose Receptor
0
Mannose-Binding Lectins
0
Receptors, Cell Surface
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2887-2898Subventions
Organisme : CIHR
ID : MOP 136802
Pays : Canada
Informations de copyright
Copyright © 2019 by The American Association of Immunologists, Inc.