Pancreatoduodenectomy
Pancreatic cancer
pancreatoduodenectomy
vascular resection
Journal
In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809
Informations de publication
Date de publication:
Historique:
received:
06
09
2019
revised:
20
09
2019
accepted:
23
09
2019
entrez:
31
10
2019
pubmed:
31
10
2019
medline:
14
3
2020
Statut:
ppublish
Résumé
Pancreatic cancer remains asymptomatic for a long period of time, being frequently diagnosed when vascular invasion is already present. Such cases are widely known as borderline lesions. The aim of this study was to identify the effectiveness of vascular resection in this subgroup of patients. Fifteen such cases were submitted to surgery with curative intent. Eight cases were diagnosed with borderline resectable lesions with portal vein invasion and were submitted to per primam resection and seven cases were initially diagnosed with arterial invasion and had been initially submitted to neoadjuvant chemotherapy followed by resection. In all cases portal vein resection was needed while in other four cases association of superior mesenteric artery resection was performed. Postoperatively, five patients developed complications requiring reoperation, three of whom died at the end of the first postoperative month. The histopathological studies confirmed the completeness of resection in all cases. Vascular resections in pancreatic cancer resections remain demanding procedures, and are reserved for cases in which a radical resection is feasible.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
Pancreatic cancer remains asymptomatic for a long period of time, being frequently diagnosed when vascular invasion is already present. Such cases are widely known as borderline lesions. The aim of this study was to identify the effectiveness of vascular resection in this subgroup of patients.
PATIENTS AND METHODS
METHODS
Fifteen such cases were submitted to surgery with curative intent.
RESULTS
RESULTS
Eight cases were diagnosed with borderline resectable lesions with portal vein invasion and were submitted to per primam resection and seven cases were initially diagnosed with arterial invasion and had been initially submitted to neoadjuvant chemotherapy followed by resection. In all cases portal vein resection was needed while in other four cases association of superior mesenteric artery resection was performed. Postoperatively, five patients developed complications requiring reoperation, three of whom died at the end of the first postoperative month. The histopathological studies confirmed the completeness of resection in all cases.
CONCLUSION
CONCLUSIONS
Vascular resections in pancreatic cancer resections remain demanding procedures, and are reserved for cases in which a radical resection is feasible.
Identifiants
pubmed: 31662572
pii: 33/6/2303
doi: 10.21873/invivo.11738
pmc: PMC6899095
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2303-2308Informations de copyright
Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
Références
Ann Surg Oncol. 2006 Aug;13(8):1035-46
pubmed: 16865597
In Vivo. 2017 Sep-Oct;31(5):983-989
pubmed: 28882970
Scand J Surg. 2017 Sep;106(3):216-223
pubmed: 28376656
In Vivo. 2018 Jul-Aug;32(4):915-919
pubmed: 29936480
J Natl Compr Canc Netw. 2017 Aug;15(8):1028-1061
pubmed: 28784865
Br J Surg. 2006 Jun;93(6):662-73
pubmed: 16703621
Acta Endocrinol (Buchar). 2018 Jul-Sep;14(3):389-393
pubmed: 31149288
J Gastrointestin Liver Dis. 2012 Sep;21(3):277-84
pubmed: 23012669
CA Cancer J Clin. 2015 Jan-Feb;65(1):5-29
pubmed: 25559415
Croat Med J. 2011 Aug 15;52(4):478-87
pubmed: 21853542
J Gastrointest Surg. 2004 Dec;8(8):935-49; discussion 949-50
pubmed: 15585381
Cancer Res. 2014 Jun 1;74(11):2913-21
pubmed: 24840647
J Am Coll Surg. 2010 Feb;210(2):e1-4
pubmed: 20113929
Anticancer Res. 2015 Mar;35(3):1613-8
pubmed: 25750318
Cancer Lett. 2016 Jun 1;375(2):231-237
pubmed: 26970276
World J Surg. 2012 Apr;36(4):884-91
pubmed: 22350478
Dig Dis. 2013;31(1):51-6
pubmed: 23797123
Am J Case Rep. 2015 Sep 19;16:637-44
pubmed: 26386552
J Oncol Pract. 2016 Oct;12(10):915-923
pubmed: 27858562
Surgery. 2014 Jun;155(6):977-88
pubmed: 24856119
Ann Surg. 2015 Jan;261(1):12-7
pubmed: 25599322
Pancreatology. 2016 Jan-Feb;16(1):28-37
pubmed: 26687001
Ann Surg. 2015 Dec;262(6):1092-101
pubmed: 25587814
In Vivo. 2018 Jul-Aug;32(4):911-914
pubmed: 29936479
Ann Surg. 1984 Apr;199(4):418-25
pubmed: 6712317
Cell. 2012 Jan 20;148(1-2):349-61
pubmed: 22265420
Future Oncol. 2019 Jun;15(17):1997-2007
pubmed: 31084373
In Vivo. 2017 Sep-Oct;31(5):979-982
pubmed: 28882969
Ann Surg. 2009 Aug;250(2):187-96
pubmed: 19638912
Br J Surg. 2012 Aug;99(8):1027-35
pubmed: 22569924
Chirurgia (Bucur). 2010 May-Jun;105(3):355-9
pubmed: 20726301
J Gastrointest Surg. 2015 Dec;19(12):2264-8
pubmed: 26423804
Nature. 2010 Oct 28;467(7319):1114-7
pubmed: 20981102
Cancer. 1980 Nov 1;46(9):1945-9
pubmed: 7427900