Long-Term Exposure to Particulate Air Pollution, Black Carbon, and Their Source Components in Relation to Ischemic Heart Disease and Stroke.


Journal

Environmental health perspectives
ISSN: 1552-9924
Titre abrégé: Environ Health Perspect
Pays: United States
ID NLM: 0330411

Informations de publication

Date de publication:
10 2019
Historique:
entrez: 31 10 2019
pubmed: 31 10 2019
medline: 25 3 2020
Statut: ppublish

Résumé

Long-term exposure to particulate matter (PM) in ambient air has been associated with cardiovascular mortality, but few studies have considered incident disease in relation to PM from different sources. We aimed to study associations between long-term exposure to different types of PM and sources, and incident ischemic heart disease (IHD) and stroke in three Swedish cities. Based on detailed emission databases, monitoring data, and high-resolution dispersion models, we calculated source contributions to PM with aerodynamic diameter We observed 5,166 and 3,119 incident IHD and stroke cases, respectively, in 114,758 participants. Overall, few consistent associations were observed between the different air pollution measures and IHD or stroke incidence. However, same-year levels of ambient locally emitted BC (range: Few consistent associations were observed between different particulate components and IHD or stroke. However, long-term residential exposure to locally emitted BC from traffic exhaust was associated with stroke incidence. The comparatively low exposure levels may have contributed to the paucity of associations. https://doi.org/10.1289/EHP4757.

Sections du résumé

BACKGROUND
Long-term exposure to particulate matter (PM) in ambient air has been associated with cardiovascular mortality, but few studies have considered incident disease in relation to PM from different sources.
OBJECTIVES
We aimed to study associations between long-term exposure to different types of PM and sources, and incident ischemic heart disease (IHD) and stroke in three Swedish cities.
METHODS
Based on detailed emission databases, monitoring data, and high-resolution dispersion models, we calculated source contributions to PM with aerodynamic diameter
RESULTS
We observed 5,166 and 3,119 incident IHD and stroke cases, respectively, in 114,758 participants. Overall, few consistent associations were observed between the different air pollution measures and IHD or stroke incidence. However, same-year levels of ambient locally emitted BC (range:
DISCUSSION
Few consistent associations were observed between different particulate components and IHD or stroke. However, long-term residential exposure to locally emitted BC from traffic exhaust was associated with stroke incidence. The comparatively low exposure levels may have contributed to the paucity of associations. https://doi.org/10.1289/EHP4757.

Identifiants

pubmed: 31663781
doi: 10.1289/EHP4757
pmc: PMC6867232
doi:

Substances chimiques

Air Pollutants 0
Particulate Matter 0
Vehicle Emissions 0
Carbon 7440-44-0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

107012

Subventions

Organisme : NIA NIH HHS
ID : R01 AG008724
Pays : United States

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Auteurs

Petter L S Ljungman (PLS)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Cardiology, Danderyd Hospital, Stockholm, Sweden.

Niklas Andersson (N)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Leo Stockfelt (L)

Department of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Eva M Andersson (EM)

Department of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Johan Nilsson Sommar (J)

Unit of Occupational and Environmental Medicine, Epidemiology and Global Health, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Kristina Eneroth (K)

SLB-analys, Environment and Health Administration, Stockholm, Sweden.

Lars Gidhagen (L)

Swedish Meteorological and Hydrological Institute, Norrköping, Sweden.

Christer Johansson (C)

SLB-analys, Environment and Health Administration, Stockholm, Sweden.
Department of Environmental Science and Analytical Chemistry, Stockholm University, Stockholm, Sweden.

Anton Lager (A)

Centre for Epidemiology and Community Medicine, Stockholm County Council, Stockholm, Sweden.
Department of Public Health Science, Karolinska Institutet, Stockholm, Sweden.

Karin Leander (K)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

Peter Molnar (P)

Department of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Nancy L Pedersen (NL)

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Debora Rizzuto (D)

Ageing Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.

Annika Rosengren (A)

Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

David Segersson (D)

Swedish Meteorological and Hydrological Institute, Norrköping, Sweden.

Patrik Wennberg (P)

Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden.

Lars Barregard (L)

Department of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Bertil Forsberg (B)

Unit of Occupational and Environmental Medicine, Epidemiology and Global Health, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

Gerd Sallsten (G)

Department of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Tom Bellander (T)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.

Göran Pershagen (G)

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden.

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