Case management of cholera.
Case management
Cholera
Treatment
Journal
Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899
Informations de publication
Date de publication:
29 02 2020
29 02 2020
Historique:
received:
24
01
2019
revised:
15
09
2019
accepted:
30
09
2019
pubmed:
2
11
2019
medline:
19
3
2021
entrez:
1
11
2019
Statut:
ppublish
Résumé
Cholera still affects about three million people a year and kills approximately 100,000. Cholera can be effectively managed in the majority of cases with oral rehydration solution alone. Up to one third of patients present with severe dehydration, which can be diagnosed clinically, and will require rapid intravenous rehydration with Ringers Lactate or other appropriate fluid before being managed with oral rehydration solution. Antibiotics reduce the duration of illness and should be used in patients with severe dehydration. Resistance is common and local sensitivities should guide the choice of antibiotic. All children between six months and five years should receive zinc supplements. Effective case management with strict attention to detail including infection control and the use of protocolized approaches can reduce the mortality to around 1% even in resource poor settings.
Identifiants
pubmed: 31668817
pii: S0264-410X(19)31342-8
doi: 10.1016/j.vaccine.2019.09.098
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Ringer's Lactate
0
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
A105-A109Informations de copyright
Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.