Case management of cholera.


Journal

Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899

Informations de publication

Date de publication:
29 02 2020
Historique:
received: 24 01 2019
revised: 15 09 2019
accepted: 30 09 2019
pubmed: 2 11 2019
medline: 19 3 2021
entrez: 1 11 2019
Statut: ppublish

Résumé

Cholera still affects about three million people a year and kills approximately 100,000. Cholera can be effectively managed in the majority of cases with oral rehydration solution alone. Up to one third of patients present with severe dehydration, which can be diagnosed clinically, and will require rapid intravenous rehydration with Ringers Lactate or other appropriate fluid before being managed with oral rehydration solution. Antibiotics reduce the duration of illness and should be used in patients with severe dehydration. Resistance is common and local sensitivities should guide the choice of antibiotic. All children between six months and five years should receive zinc supplements. Effective case management with strict attention to detail including infection control and the use of protocolized approaches can reduce the mortality to around 1% even in resource poor settings.

Identifiants

pubmed: 31668817
pii: S0264-410X(19)31342-8
doi: 10.1016/j.vaccine.2019.09.098
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Ringer's Lactate 0
Zinc J41CSQ7QDS

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

A105-A109

Informations de copyright

Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

M A C Pietroni (MAC)

Medical Director, Gloucetsershire Royal Hospitals NHS Foundation Trust, Gloucester, UK; University of Bristol, Faculty of Health Sciences, Bristol, UK. Electronic address: mark.pietroni@nhs.net.

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Classifications MeSH