Clinical Predictors and Prognostic Impact of Recovery of Wall Motion Abnormalities in Takotsubo Syndrome: Results From the International Takotsubo Registry.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
05 11 2019
Historique:
entrez: 2 11 2019
pubmed: 2 11 2019
medline: 15 12 2020
Statut: ppublish

Résumé

Background Left ventricular (LV) recovery in takotsubo syndrome (TTS) occurs over a wide-ranging interval, varying from hours to weeks. We sought to investigate the clinical predictors and prognostic impact of recovery time for TTS patients. Methods and Results TTS patients from the International Takotsubo Registry were included in this study. Cut-off for early LV recovery was determined to be 10 days after the acute event. Multivariable logistic regression was used to assess factors associated with the absence of early recovery. In-hospital outcomes and 1-year mortality were compared for patients with versus without early recovery. We analyzed 406 patients with comprehensive and serial imaging data regarding time to recovery. Of these, 191 (47.0%) had early LV recovery and 215 (53.0%) demonstrated late LV improvement. Patients without early recovery were more often male (12.6% versus 5.2%;

Identifiants

pubmed: 31672100
doi: 10.1161/JAHA.118.011194
pmc: PMC6898832
doi:

Banques de données

ClinicalTrials.gov
['NCT01947621']

Types de publication

Comparative Study Journal Article Multicenter Study Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e011194

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Auteurs

Stjepan Jurisic (S)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

Sebastiano Gili (S)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.
Centro Cardiologico Monzino IRCCS Milan Italy.

Victoria L Cammann (VL)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

Ken Kato (K)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.
Department of Cardiovascular Medicine Chiba University Graduate School of Medicine Chiba Japan.

Konrad A Szawan (KA)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

Fabrizio D'Ascenzo (F)

Division of Cardiology Department of Medical Sciences AOU Città della Salute e della Scienza University of Turin Italy.

Milosz Jaguszewski (M)

First Department of Cardiology Medical University of Gdansk Poland.

Eduardo Bossone (E)

Heart Department University Hospital "San Giovanni di Dio e Ruggi d'Aragona" Salerno Italy.

Rodolfo Citro (R)

Heart Department University Hospital "San Giovanni di Dio e Ruggi d'Aragona" Salerno Italy.

Annahita Sarcon (A)

University of Southern California, Keck School of Medicine Los Angeles CA.

L Christian Napp (LC)

Department of Cardiology and Angiology Hannover Medical School Hannover Germany.

Jennifer Franke (J)

Department of Cardiology Heidelberg University Hospital Heidelberg Germany.

Michel Noutsias (M)

Division of Cardiology, Angiology and Intensive Medical Care Department of Internal Medicine III University Hospital Halle Martin-Luther-University Halle Halle (Saale) Germany.

Maike Knorr (M)

Center for Cardiology Cardiology 1 University Medical Center Mainz Mainz Germany.

Susanne Heiner (S)

Center for Cardiology Cardiology 1 University Medical Center Mainz Mainz Germany.

Christof Burgdorf (C)

Heart and Vascular Centre Bad Bevensen Bad Bevensen Germany.

Wolfgang Koenig (W)

Deutsches Herzzentrum München Technische Universität München Munich Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance Munich Germany.

Alexander Pott (A)

Department of Internal Medicine II-Cardiology University of Ulm, Medical Center Ulm Germany.

Behrouz Kherad (B)

Department of Cardiology Charité, Campus Rudolf Virchow Berlin Germany.

Lawrence Rajan (L)

TJ Health Partners Heart and Vascular Glasgow KY.

Guido Michels (G)

Department of Internal Medicine III Heart Center University of Cologne Germany.

Roman Pfister (R)

Department of Internal Medicine III Heart Center University of Cologne Germany.

Alessandro Cuneo (A)

Krankenhaus "Maria Hilf" Medizinische Klinik Stadtlohn Germany.

Claudius Jacobshagen (C)

Clinic for Cardiology and Pneumology Georg August University Goettingen Goettingen Germany.

Mahir Karakas (M)

Department of General and Interventional Cardiology University Heart Center Hamburg Hamburg Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Luebeck Hamburg Germany.

Philippe Meyer (P)

Service de cardiologie Hôpitaux Universitaires de Genève Geneva Switzerland.

Jose David Arroja (JD)

Service de cardiologie Hôpitaux Universitaires de Genève Geneva Switzerland.

Adrian Banning (A)

Department of Cardiology John Radcliffe Hospital Oxford University Hospitals Oxford United Kingdom.

Florim Cuculi (F)

Department of Cardiology Kantonsspital Lucerne Lucerne Switzerland.

Richard Kobza (R)

Department of Cardiology Kantonsspital Lucerne Lucerne Switzerland.

Thomas A Fischer (TA)

Department of Cardiology Kantonsspital Winterthur Winterthur Switzerland.

Tuija Vasankari (T)

Heart Center Turku University Hospital and University of Turku Turku Finland.

K E Juhani Airaksinen (KEJ)

Heart Center Turku University Hospital and University of Turku Turku Finland.

Rafal Dworakowski (R)

Department of Cardiology Kings College Hospital Kings Health Partners London United Kingdom.

Christoph Kaiser (C)

Department of Cardiology University Hospital Basel Basel Switzerland.

Stefan Osswald (S)

Department of Cardiology University Hospital Basel Basel Switzerland.

Leonarda Galiuto (L)

Department of Cardiovascular Sciences Catholic University of the Sacred Heart Rome Rome Italy.

Wolfgang Dichtl (W)

University Hospital for Internal Medicine III (Cardiology and Angiology) Medical University Innsbruck Innsbruck Austria.

Christina Chan (C)

Department of Cardiology Christchurch Hospital Christchurch New Zealand.

Paul Bridgman (P)

Department of Cardiology Christchurch Hospital Christchurch New Zealand.

Daniel Beug (D)

Department of Internal Medicine B University Medicine Greifswald Greifswald Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald Greifswald Germany.

Clément Delmas (C)

Department of Cardiology and Cardiac Imaging Center University Hospital of Rangueil Toulouse France.

Olivier Lairez (O)

Department of Cardiology and Cardiac Imaging Center University Hospital of Rangueil Toulouse France.

Martin Kozel (M)

Charles University in Prague and University Hospital Kralovske Vinohrady Prague Czech Republic.

Petr Tousek (P)

Charles University in Prague and University Hospital Kralovske Vinohrady Prague Czech Republic.

David E Winchester (DE)

Department of Medicine College of Medicine University of Florida Gainesville FL.

Ekaterina Gilyarova (E)

Intensive Coronary Care Unit Moscow City Hospital # 1 named after N. Pirogov Moscow Russia.

Alexandra Shilova (A)

Intensive Coronary Care Unit Moscow City Hospital # 1 named after N. Pirogov Moscow Russia.

Mikhail Gilyarov (M)

Intensive Coronary Care Unit Moscow City Hospital # 1 named after N. Pirogov Moscow Russia.

Ibrahim El-Battrawy (I)

First Department of Medicine Faculty of Medicine University Medical Centre Mannheim (UMM) University of Heidelberg Mannheim Germany.
DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim Mannheim Germany.

Ibrahim Akin (I)

First Department of Medicine Faculty of Medicine University Medical Centre Mannheim (UMM) University of Heidelberg Mannheim Germany.
DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim Mannheim Germany.

Jan Galuszka (J)

Department of Internal Medicine I - Cardiology University Hospital Olomouc Olomouc Czech Republic.

Christian Ukena (C)

Klinik für Innere Medizin III Universitätsklinikum des Saarlandes Homburg/Saar Germany.

Gregor Poglajen (G)

Advanced Heart Failure and Transplantation Center University Medical Center Ljubljana Ljubljana Slovenia.

Carla Paolini (C)

Local Health Unit n.8, Cardiology Unit Arzignano Vicenza Italy.

Claudio Bilato (C)

Local Health Unit n.8, Cardiology Unit Arzignano Vicenza Italy.

Pedro Carrilho-Ferreira (P)

Cardiology Department Santa Maria University Hospital (CHLN) Lisbon Academic Medical Centre and Cardiovascular Centre of the University of Lisbon (CCUL) Lisbon School of Medicine Universidade de Lisboa Portugal.

Fausto J Pinto (FJ)

Cardiology Department Santa Maria University Hospital (CHLN) Lisbon Academic Medical Centre and Cardiovascular Centre of the University of Lisbon (CCUL) Lisbon School of Medicine Universidade de Lisboa Portugal.

Grzegorz Opolski (G)

Department of Cardiology Medical University of Warsaw Poland.

Philip MacCarthy (P)

Department of Cardiology Kings College Hospital Kings Health Partners London United Kingdom.

Yoshio Kobayashi (Y)

Department of Cardiovascular Medicine Chiba University Graduate School of Medicine Chiba Japan.

Abhiram Prasad (A)

Division of Cardiovascular Diseases Mayo Clinic Rochester MN.

Charanjit S Rihal (CS)

Division of Cardiovascular Diseases Mayo Clinic Rochester MN.

Petr Widimský (P)

Charles University in Prague and University Hospital Kralovske Vinohrady Prague Czech Republic.

John D Horowitz (JD)

Department of Cardiology Basil Hetzel Institute Queen Elizabeth Hospital University of Adelaide Australia.

Carlo Di Mario (C)

University Hospital Careggi Florence Italy.

Filippo Crea (F)

Fondazione Policlinico Universitario A. Gemelli IRCCS Roma Italy.

Carsten Tschöpe (C)

Department of Cardiology Charité, Campus Rudolf Virchow Berlin Germany.

Burkert M Pieske (BM)

Department of Cardiology Charité, Campus Rudolf Virchow Berlin Germany.
DZHK (German Center for Cardiovascular Research), Partner Site Berlin Berlin Germany.
Berlin Institute of Health (BIH) Berlin Germany.

Gerd Hasenfuß (G)

Clinic for Cardiology and Pneumology Georg August University Goettingen Goettingen Germany.

Wolfgang Rottbauer (W)

Department of Internal Medicine II-Cardiology University of Ulm, Medical Center Ulm Germany.

Ruediger C Braun-Dullaeus (RC)

Internal Medicine/Cardiology, Angiology, and Pneumology Magdeburg University Magdeburg Germany.

Stephan B Felix (SB)

Department of Internal Medicine B University Medicine Greifswald Greifswald Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald Greifswald Germany.

Martin Borggrefe (M)

First Department of Medicine Faculty of Medicine University Medical Centre Mannheim (UMM) University of Heidelberg Mannheim Germany.
DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim Mannheim Germany.

Holger Thiele (H)

Department of Internal Medicine/Cardiology Heart Center Leipzig-University Hospital Leipzig Germany.

Johann Bauersachs (J)

Department of Cardiology and Angiology Hannover Medical School Hannover Germany.

Hugo A Katus (HA)

Department of Cardiology Heidelberg University Hospital Heidelberg Germany.

Heribert Schunkert (H)

Deutsches Herzzentrum München Technische Universität München Munich Germany.
DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance Munich Germany.

Thomas Münzel (T)

Center for Cardiology Cardiology 1 University Medical Center Mainz Mainz Germany.

Michael Böhm (M)

Klinik für Innere Medizin III Universitätsklinikum des Saarlandes Homburg/Saar Germany.

Jeroen J Bax (JJ)

Department of Cardiology Leiden University Medical Centre Leiden The Netherlands.

Thomas F Lüscher (TF)

Center for Molecular Cardiology Schlieren Campus University of Zurich Switzerland.
Cardiology Royal Brompton and Harefield Hospitals Trust and Imperial College London United Kingdom.

Frank Ruschitzka (F)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

Jelena R Ghadri (JR)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

Christian Templin (C)

University Heart Center Department of Cardiology University Hospital Zurich Zurich Switzerland.

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