The Respiratory Syncytial Virus Polymerase: A Multitasking Machine.

capping methyltransferase mononegavirales polymerase respiratory syncytial virus transcription

Journal

Trends in microbiology
ISSN: 1878-4380
Titre abrégé: Trends Microbiol
Pays: England
ID NLM: 9310916

Informations de publication

Date de publication:
12 2019
Historique:
received: 30 09 2019
accepted: 07 10 2019
pubmed: 2 11 2019
medline: 21 5 2020
entrez: 2 11 2019
Statut: ppublish

Résumé

Respiratory syncytial virus (RSV) inflicts a significant toll on human life. An essential element of the virus is its polymerase, a complex capable of transcribing and replicating the viral genome. In an exciting new advance, Gilman et al. resolve the structure of this polymerase, providing valuable mechanistic insight into its activities.

Identifiants

pubmed: 31672264
pii: S0966-842X(19)30253-7
doi: 10.1016/j.tim.2019.10.001
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

969-971

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI113321
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI133486
Pays : United States
Organisme : NHLBI NIH HHS
ID : R33 HL137081
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Rachel Fearns (R)

Department of Microbiology, National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, 620 Albany Street, Boston, MA 02118, USA. Electronic address: rfearns@bu.edu.

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Classifications MeSH