A Diagnostic Approach to Adrenocortical Tumors.

Adrenal cortical adenoma Adrenal cortical carcinoma Adrenal gland Cushing syndrome IGF-2 Nodular cortical disease Primary aldosteronism Virilism and feminization

Journal

Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209

Informations de publication

Date de publication:
Dec 2019
Historique:
entrez: 2 11 2019
pubmed: 2 11 2019
medline: 7 7 2020
Statut: ppublish

Résumé

Adrenocortical tumors range from primary bilateral micronodular or macronodular forms of adrenocortical disease to conventional adrenocortical adenomas and carcinomas. Accurate classification of these neoplasms is critical given the varied pathogenesis, clinical behavior, and outcome of these different lesions. Confirmation of adrenocortical origin, diagnosing malignancy, providing relevant prognostic information in adrenocortical carcinoma, and correlation of laboratory results with clinicopathologic findings are among the important responsibilities of pathologists who evaluate these lesions. This article focuses on a practical approach to the evaluation of adrenocortical tumors with an emphasis on clinical and imaging findings, morphologic characteristics, and multifactorial diagnostic schemes and algorithms.

Identifiants

pubmed: 31672302
pii: S1875-9181(19)30061-3
doi: 10.1016/j.path.2019.08.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

967-995

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Anjelica Hodgson (A)

Department of Laboratory Medicine and Pathobiology, The University of Toronto, 1 King's College Circle, Medical Sciences Building, Toronto, Ontario M5S1A8, Canada.

Sara Pakbaz (S)

Department of Pathology, University Health Network, The University of Toronto, 200 Elizabeth Street, 11th Floor, Toronto, Ontario M5G2C4, Canada.

Ozgur Mete (O)

Department of Pathology, University Health Network, 200 Elizabeth Street, 11th Floor, Toronto, Ontario M5G2C4, Canada; Department of Laboratory Medicine and Pathobiology, The University of Toronto, Toronto, Ontario, Canada. Electronic address: ozgur.mete2@uhn.ca.

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Classifications MeSH