Phosphorylation of the Gα protein Gpa2 promotes protein kinase A signaling in yeast.
Cell Membrane
/ metabolism
Cyclic AMP-Dependent Protein Kinases
/ genetics
GTP-Binding Protein alpha Subunits
/ genetics
Gene Expression Regulation, Fungal
Glycogen Synthase Kinases
/ genetics
Phosphorylation
Saccharomyces cerevisiae
/ genetics
Saccharomyces cerevisiae Proteins
/ genetics
Signal Transduction
G protein
Gpa2
PKA
cellular localization
glycogen synthase kinase
nutrient signaling
posttranslational modification (PTM)
protein kinase
protein phosphorylation
sporulation
yeast
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
06 12 2019
06 12 2019
Historique:
received:
30
05
2019
revised:
31
10
2019
pubmed:
7
11
2019
medline:
17
6
2020
entrez:
7
11
2019
Statut:
ppublish
Résumé
Heterotrimeric G proteins are important molecular switches that facilitate transmission of a variety of signals from the outside to the inside of cells. G proteins are highly conserved, enabling study of their regulatory mechanisms in model organisms such as the budding yeast
Identifiants
pubmed: 31690628
pii: S0021-9258(20)30432-4
doi: 10.1074/jbc.RA119.009609
pmc: PMC6901295
pii:
doi:
Substances chimiques
GTP-Binding Protein alpha Subunits
0
Saccharomyces cerevisiae Proteins
0
Glycogen Synthase Kinases
EC 2.7.11.-
Cyclic AMP-Dependent Protein Kinases
EC 2.7.11.11
Gpa2 protein, S cerevisiae
EC 3.6.5.1
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
18836-18845Subventions
Organisme : NIGMS NIH HHS
ID : R15 GM128047
Pays : United States
Informations de copyright
© 2019 Huang et al.
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