Impact of emotion dysregulation and cognitive insight on psychotic and depressive symptoms during the early course of schizophrenia spectrum disorders.


Journal

Early intervention in psychiatry
ISSN: 1751-7893
Titre abrégé: Early Interv Psychiatry
Pays: Australia
ID NLM: 101320027

Informations de publication

Date de publication:
12 2020
Historique:
received: 01 03 2019
revised: 24 09 2019
accepted: 19 10 2019
pubmed: 7 11 2019
medline: 7 7 2021
entrez: 7 11 2019
Statut: ppublish

Résumé

Emotion dysregulation is relevant to the aetiology of schizophrenia spectrum disorders (SSD). While most studies have focused on the chronic phase of SSD, little is known about the effects of emotion dysregulation and associated cognitive risk factors during the early phase of the illness, with negative implications for early intervention. The purpose of this study is to examine the impact of maladaptive cognitive emotion regulation strategies, global emotion dysregulation, and cognitive insight on psychotic and comorbid depressive symptoms in patients with early SSD. Participants included 150 newly diagnosed outpatients with SSD who were seeking treatment at the Early Psychosis Intervention Program. All participants completed the Cognitive Emotion Regulation Questionnaire, Difficulties with Emotion Regulation Scale, and Beck Cognitive Insight Scale. Severity of psychotic and depressive symptoms were rated on the Brief Psychiatric Rating Scale. Multivariate regression adjusting for gender and psychiatric comorbidity revealed that global emotion dysregulation was associated with more severe positive and depressive symptoms. Further moderation analyses revealed a significant interaction between global emotion dysregulation and cognitive insight (self-certainty) on depression such that for patients with high self-certainty, greater global emotion dysregulation was associated with increased severity of depressive symptoms. There was no interaction between global emotion dysregulation and cognitive insight on positive symptoms. Our findings provide preliminary support for the associations between emotion dysregulation and psychopathology in early SSD. Further research is needed to examine the transdiagnostic role of emotion dysregulation in the aetiology and treatment of a wider range of psychotic disorders.

Identifiants

pubmed: 31692276
doi: 10.1111/eip.12895
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

691-697

Subventions

Organisme : Institute of Mental Health Research Grant
ID : CRC Ref No 569-2017
Pays : International

Informations de copyright

© 2019 John Wiley & Sons Australia, Ltd.

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Auteurs

Jianlin Liu (J)

Department of Psychological Medicine, National University of Singapore, Singapore, Singapore.
Research Division, Institute of Mental Health, Singapore, Singapore.

Tommy C T Chan (TCT)

Department of Early Psychosis Intervention, Institute of Mental Health, Singapore, Singapore.

Siow Ann Chong (SA)

Research Division, Institute of Mental Health, Singapore, Singapore.

Mythily Subramaniam (M)

Research Division, Institute of Mental Health, Singapore, Singapore.

Rathi Mahendran (R)

Department of Psychological Medicine, National University of Singapore, Singapore, Singapore.
Duke-NUS Medical School, Singapore, Singapore.

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