Adherence to and outcomes of a University-Consortium gastroschisis pathway.


Journal

Journal of pediatric surgery
ISSN: 1531-5037
Titre abrégé: J Pediatr Surg
Pays: United States
ID NLM: 0052631

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 12 09 2019
accepted: 29 09 2019
pubmed: 11 11 2019
medline: 4 9 2020
entrez: 10 11 2019
Statut: ppublish

Résumé

Our multi-institutional university consortium implemented a gastroschisis pathway in 2015 to standardize and improve care by promoting avoidance of routine intubation and paralysis during silo placement, expeditious abdominal wall closure, discontinuation of antibiotics/narcotics within 48 h of closure, and early initiation/advancement of feeds. Adherence to the gastroschisis pathway was prospectively monitored. Outcomes for the contemporary cohort (2015-2018) were compared with a historical cohort (2007-2012). Good adherence to the pathway was observed for 70 cases of inborn uncomplicated gastroschisis. The contemporary cohort had significantly lower median mechanical ventilator days (2 versus 5; p < 0.01) and antibiotic days (5.5 versus 9; p < 0.01) as well as earlier days to initiation of feeds (12 versus 15; p < 0.01). However, no differences were observed in length of stay (28 versus 29 days; p = 0.70). A skin closure technique was performed in 66% of the patients, of which 46% were performed at bedside without intubation, the assistance of an operating-room team, or general anesthesia. In this study, adherence to a clinical pathway for gastroschisis across different facilities was feasible and led to reduction in exposure to mechanical ventilation and antibiotics. The adoption of a bedside skin closure technique appears to facilitate compliance with the pathway. Level II/III TYPE OF STUDY: Prospective comparative study with historical cohort.

Sections du résumé

BACKGROUND BACKGROUND
Our multi-institutional university consortium implemented a gastroschisis pathway in 2015 to standardize and improve care by promoting avoidance of routine intubation and paralysis during silo placement, expeditious abdominal wall closure, discontinuation of antibiotics/narcotics within 48 h of closure, and early initiation/advancement of feeds.
METHODS METHODS
Adherence to the gastroschisis pathway was prospectively monitored. Outcomes for the contemporary cohort (2015-2018) were compared with a historical cohort (2007-2012).
RESULTS RESULTS
Good adherence to the pathway was observed for 70 cases of inborn uncomplicated gastroschisis. The contemporary cohort had significantly lower median mechanical ventilator days (2 versus 5; p < 0.01) and antibiotic days (5.5 versus 9; p < 0.01) as well as earlier days to initiation of feeds (12 versus 15; p < 0.01). However, no differences were observed in length of stay (28 versus 29 days; p = 0.70). A skin closure technique was performed in 66% of the patients, of which 46% were performed at bedside without intubation, the assistance of an operating-room team, or general anesthesia.
CONCLUSION CONCLUSIONS
In this study, adherence to a clinical pathway for gastroschisis across different facilities was feasible and led to reduction in exposure to mechanical ventilation and antibiotics. The adoption of a bedside skin closure technique appears to facilitate compliance with the pathway.
LEVEL OF EVIDENCE METHODS
Level II/III TYPE OF STUDY: Prospective comparative study with historical cohort.

Identifiants

pubmed: 31704046
pii: S0022-3468(19)30701-8
doi: 10.1016/j.jpedsurg.2019.09.048
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

45-48

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Daniel A DeUgarte (DA)

University of California - Los Angeles. Electronic address: ddeugarte@mednet.ucla.edu.

Kara L Calkins (KL)

University of California - Los Angeles.

Yigit Guner (Y)

University of California - Irvine.

Jae Kim (J)

University of California - San Diego.

Karen Kling (K)

University of California - San Diego.

Katelin Kramer (K)

University of California - San Francisco.

Hanmin Lee (H)

University of California - San Francisco.

Leslie Lusk (L)

University of California - San Francisco.

Payam Saadai (P)

University of California - Davis.

Cherry Uy (C)

University of California - Irvine.

Catherine Rottkamp (C)

University of California - Davis.

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