Exosomes derived from mesenchymal stem cells improved function and survival of neutrophils from severe congenital neutropenia patients in vitro.

Adipose Tissue / pathology Adult Apoptosis Cells, Cultured Congenital Bone Marrow Failure Syndromes / pathology Culture Media, Conditioned / metabolism Exosomes / pathology Humans Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells / pathology Neutropenia / congenital Neutrophils / pathology Phagocytosis
Apoptosis Exosomes Mesenchymal stem cells Neutrophils Severe congenital neutropenia

Journal

Human immunology
ISSN: 1879-1166
Titre abrégé: Hum Immunol
Pays: United States
ID NLM: 8010936

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 05 08 2019
revised: 28 09 2019
accepted: 28 10 2019
pubmed: 11 11 2019
medline: 28 3 2020
entrez: 11 11 2019
Statut: ppublish

Résumé

Severe congenital neutropenia (SCN) is described by the absolute neutrophil counts less than 500 cells/mm

Identifiants

DOI: 10.1016/j.humimm.2019.10.006 PMID: 31706743
pubmed: 31706743
pii: S0198-8859(19)31057-2
doi: 10.1016/j.humimm.2019.10.006
pii:
doi:

Substances chimiques

Culture Media, Conditioned 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

990-998

Informations de copyright

Copyright © 2019 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

Auteurs

Mohammad Mahmoudi (M)

Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mahsa Taghavi-Farahabadi (M)

Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Saeed Namaki (S)

Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Kaveh Baghaei (K)

Basic and Molecular Epidemiology of Gastrointestinal Disorder Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran.

Elham Rayzan (E)

International Hematology/Oncology of Pediatrics Experts, Universal Scientific Education and Research Network, Tehran University of Medical Sciences, Iran.

Nima Rezaei (N)

Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Sheffield, UK.

Seyed Mahmoud Hashemi (SM)

Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Urogenital Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: smmhashemi@sbmu.ac.ir.

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Classifications MeSH

questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Cellules › Cellules cultivées › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Insuffisances médullaires congénitales › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Équipement et fournitures › Milieux de culture › Milieux de culture conditionnés › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Exosomes › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation cellulaire › Transplantation de cellules souches › Transplantation de cellules souches mésenchymateuses › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Cellules › Cellules souches › Cellules souches multipotentes › Cellules souches mésenchymateuses › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Troubles leucocytaires › Leucopénie › Agranulocytose › Neutropénie › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Phagocytes › Granulocytes neutrophiles › Exosomes derived from mesenchymal stem cells...
questionsmedicales.fr › Phénomènes du système immunitaire › Phagocytose › Exosomes derived from mesenchymal stem cells...