Durable response to palbociclib and letrozole in ovarian cancer with
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Biomarkers, Tumor
/ genetics
Cyclin E
/ genetics
Cyclin-Dependent Kinase Inhibitor p16
/ genetics
Cystadenocarcinoma, Serous
/ drug therapy
Female
Gene Amplification
Humans
Letrozole
/ administration & dosage
Middle Aged
Neoplasm Recurrence, Local
/ drug therapy
Oncogene Proteins
/ genetics
Ovarian Neoplasms
/ drug therapy
Piperazines
/ administration & dosage
Prognosis
Pyridines
/ administration & dosage
Retinoblastoma Binding Proteins
/ genetics
Sequence Deletion
Ubiquitin-Protein Ligases
/ genetics
CDK4/6 inhibitors
CDKN2A loss
Ovarian cancer
palbociblib
precision oncology
Journal
Cancer biology & therapy
ISSN: 1555-8576
Titre abrégé: Cancer Biol Ther
Pays: United States
ID NLM: 101137842
Informations de publication
Date de publication:
2020
2020
Historique:
pubmed:
12
11
2019
medline:
6
7
2021
entrez:
12
11
2019
Statut:
ppublish
Résumé
Alterations of the Retinoblastoma (Rb) pathway are frequent in ovarian cancer, typically resulting from
Identifiants
pubmed: 31709901
doi: 10.1080/15384047.2019.1685291
pmc: PMC7012162
doi:
Substances chimiques
Biomarkers, Tumor
0
CCNE1 protein, human
0
CDKN2A protein, human
0
Cyclin E
0
Cyclin-Dependent Kinase Inhibitor p16
0
Oncogene Proteins
0
Piperazines
0
Pyridines
0
RB1 protein, human
0
Retinoblastoma Binding Proteins
0
Letrozole
7LKK855W8I
Ubiquitin-Protein Ligases
EC 2.3.2.27
palbociclib
G9ZF61LE7G
Types de publication
Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
197-202Références
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