Early pregnancy vitamin D deficiency and gestational diabetes: Exploring the link.
Journal
Australian journal of general practice
ISSN: 2208-7958
Titre abrégé: Aust J Gen Pract
Pays: Australia
ID NLM: 101718099
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
entrez:
14
11
2019
pubmed:
15
11
2019
medline:
28
8
2020
Statut:
ppublish
Résumé
Diabetes, including gestational diabetes mellitus (GDM), and vitamin D deficiency or insufficiency (VDDI) are recognised public health problems. There is conflicting evidence regarding the relationship between vitamin D deficiency and GDM. The aim of this study was to explore the incidence of VDDI among pregnant women attending a maternity unit in Sydney, Australia, and the relationship between VDDI in early pregnancy and later development of GDM. This was a prospective cohort study in which 25-hydroxyvitamin D was measured in pregnant women during 2011-13. Exclusion criteria included pre existing diabetes, bowel disease and reduced cognitive ability. There were 785 women enrolled in the study and 42 excluded. Findings from this study did not show an association between VDDI in early pregnancy and development of GDM. Important predictors of GDM remained the well known risk factors: family history, ethnicity, body mass index and age. Clinical conversations should continue to focus on proven modifiable factors such as weight management and the provision of timely testing appropriate to the risk identified through history-taking.
Sections du résumé
BACKGROUND AND OBJECTIVES
Diabetes, including gestational diabetes mellitus (GDM), and vitamin D deficiency or insufficiency (VDDI) are recognised public health problems. There is conflicting evidence regarding the relationship between vitamin D deficiency and GDM. The aim of this study was to explore the incidence of VDDI among pregnant women attending a maternity unit in Sydney, Australia, and the relationship between VDDI in early pregnancy and later development of GDM.
METHOD
This was a prospective cohort study in which 25-hydroxyvitamin D was measured in pregnant women during 2011-13. Exclusion criteria included pre existing diabetes, bowel disease and reduced cognitive ability.
RESULTS
There were 785 women enrolled in the study and 42 excluded. Findings from this study did not show an association between VDDI in early pregnancy and development of GDM. Important predictors of GDM remained the well known risk factors: family history, ethnicity, body mass index and age.
DISCUSSION
Clinical conversations should continue to focus on proven modifiable factors such as weight management and the provision of timely testing appropriate to the risk identified through history-taking.
Identifiants
pubmed: 31722465
doi: 10.31128/AJGP-09-18-469
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM