Activity of caspase-8 determines plasticity between cell death pathways.
Animals
CARD Signaling Adaptor Proteins
/ metabolism
Caspase 8
/ genetics
Cell Death
/ genetics
Female
Gene Expression Regulation
HEK293 Cells
Humans
Intestinal Mucosa
/ cytology
Kaplan-Meier Estimate
Male
Mice
Mice, Inbred C57BL
Mutation
Receptor-Interacting Protein Serine-Threonine Kinases
/ metabolism
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
11 2019
11 2019
Historique:
received:
12
02
2019
accepted:
26
09
2019
pubmed:
15
11
2019
medline:
14
4
2020
entrez:
15
11
2019
Statut:
ppublish
Résumé
Caspase-8 is a protease with both pro-death and pro-survival functions: it mediates apoptosis induced by death receptors such as TNFR1
Identifiants
pubmed: 31723262
doi: 10.1038/s41586-019-1752-8
pii: 10.1038/s41586-019-1752-8
doi:
Substances chimiques
CARD Signaling Adaptor Proteins
0
Pycard protein, mouse
0
Receptor-Interacting Protein Serine-Threonine Kinases
EC 2.7.11.1
Ripk3 protein, mouse
EC 2.7.11.1
Caspase 8
EC 3.4.22.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
679-682Références
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