Rohit Reja

Affiliations

Oncology Bioinformatics, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Publications (13)

N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation.

Immunity

Avec: Alexander D Gitlin , Allie Maltzman , Yuzuka Kanno , Klaus Heger , Rohit Reja , Alexander F Schubert , Linsey J Wierciszewski , Homer Pantua , Sharookh B Kapadia , Seth F Harris , Joshua D Webster , Kim Newton , Vishva M Dixit

Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia.

Cell

Avec: Ada Ndoja , Rohit Reja , Seung-Hye Lee , Joshua D Webster , Hai Ngu , Christopher M Rose , Donald S Kirkpatrick , Zora Modrusan , Ying-Jiun Jasmine Chen , Debra L Dugger , Vineela Gandham , Luke Xie , Kim Newton , Vishva M Dixit

Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.

Cell host & microbe

Avec: Giovanni Luchetti , Justin L Roncaioli , Roberto A Chavez , Alexander F Schubert , Eric M Kofoed , Rohit Reja , Tommy K Cheung , Yuxin Liang , Joshua D Webster , Isabelle Lehoux , Elizabeth Skippington , Janina Reeder , Benjamin Haley , Man Wah Tan , Christopher M Rose , Kim Newton , Nobuhiko Kayagaki , Russell E Vance , Vishva M Dixit

The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.

PloS one

Avec: Mona Abed , Erik Verschueren , Hanna Budayeva , Peter Liu , Donald S Kirkpatrick , Rohit Reja , Sarah K Kummerfeld , Joshua D Webster , Sarah Gierke , Mike Reichelt , Keith R Anderson , Robert J Newman , Merone Roose-Girma , Zora Modrusan , Hazal Pektas , Emin Maltepe , Kim Newton , Vishva M Dixit

The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.

Nature

Avec: Nina Oberbeck , Victoria C Pham , Joshua D Webster , Rohit Reja , Christine S Huang , Yue Zhang , Merone Roose-Girma , Søren Warming , Qingling Li , Andrew Birnberg , Weng Wong , Wendy Sandoval , László G Kőműves , Kebing Yu , Debra L Dugger , Allie Maltzman , Kim Newton , Vishva M Dixit

Integration of innate immune signalling by caspase-8 cleavage of N4BP1.

Nature

Avec: Alexander D Gitlin , Klaus Heger , Alexander F Schubert , Rohit Reja , Donghong Yan , Victoria C Pham , Eric Suto , Juan Zhang , Youngsu C Kwon , Emily C Freund , Jing Kang , Anna Pham , Roger Caothien , Natasha Bacarro , Trent Hinkle , Min Xu , Brent S McKenzie , Benjamin Haley , Wyne P Lee , Jennie R Lill , Merone Roose-Girma , Monika Dohse , Joshua D Webster , Kim Newton , Vishva M Dixit

IRF2 transcriptionally induces

Science signaling

Avec: Nobuhiko Kayagaki , Bettina L Lee , Irma B Stowe , Opher S Kornfeld , Karen O'Rourke , Kathleen M Mirrashidi , Benjamin Haley , Colin Watanabe , Merone Roose-Girma , Zora Modrusan , Sarah Kummerfeld , Rohit Reja , Yafei Zhang , Vicky Cho , T Daniel Andrews , Lucy X Morris , Christopher C Goodnow , Edward M Bertram , Vishva M Dixit

Activity of caspase-8 determines plasticity between cell death pathways.

Nature

Avec: Kim Newton , Katherine E Wickliffe , Allie Maltzman , Debra L Dugger , Rohit Reja , Yue Zhang , Merone Roose-Girma , Zora Modrusan , Meredith S Sagolla , Joshua D Webster , Vishva M Dixit

Actin R256 Mono-methylation Is a Conserved Post-translational Modification Involved in Transcription.

Cell reports

Avec: Ashok Kumar , Yuan Zhong , Amelie Albrecht , Pau Biak Sang , Adrian Maples , Zhenan Liu , Vinesh Vinayachandran , Rohit Reja , Chia-Fang Lee , Ashutosh Kumar , Jiyuan Chen , Jing Xiao , Bongsoo Park , Jianjun Shen , Bin Liu , Maria D Person , Kathleen M Trybus , Kam Y J Zhang , B Franklin Pugh , Kristine E Kamm , Dianna M Milewicz , Xuetong Shen , Prabodh Kapoor

NINJ1 mediates plasma membrane rupture during lytic cell death.

Nature

Avec: Nobuhiko Kayagaki , Opher S Kornfeld , Bettina L Lee , Irma B Stowe , Karen O'Rourke , Qingling Li , Wendy Sandoval , Donghong Yan , Jing Kang , Min Xu , Juan Zhang , Wyne P Lee , Brent S McKenzie , Gözde Ulas , Jian Payandeh , Merone Roose-Girma , Zora Modrusan , Rohit Reja , Meredith Sagolla , Joshua D Webster , Vicky Cho , T Daniel Andrews , Lucy X Morris , Lisa A Miosge , Christopher C Goodnow , Edward M Bertram , Vishva M Dixit

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling.

Cell reports

Avec: Jeffrey K Holden , James J Crawford , Cameron L Noland , Stephen Schmidt , Jason R Zbieg , Jennifer A Lacap , Richard Zang , Gregory M Miller , Yue Zhang , Paul Beroza , Rohit Reja , Wendy Lee , Jeffrey Y K Tom , Rina Fong , Micah Steffek , Saundra Clausen , Thjis J Hagenbeek , Taishan Hu , Zheng Zhou , Hong C Shen , Christian N Cunningham

Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.

Science (New York, N.Y.)

Avec: Meng He , Mira S Chaurushiya , Joshua D Webster , Sarah Kummerfeld , Rohit Reja , Subhra Chaudhuri , Ying-Jiun Chen , Zora Modrusan , Benjamin Haley , Debra L Dugger , Jeffrey Eastham-Anderson , Shari Lau , Anwesha Dey , Roger Caothien , Merone Roose-Girma , Kim Newton , Vishva M Dixit

ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1.

Cell death and differentiation

Avec: Margaret Solon , Nianfeng Ge , Shannon Hambro , Susan Haller , Jian Jiang , Miriam Baca , Jessica Preston , Allie Maltzman , Katherine E Wickliffe , Yuxin Liang , Rohit Reja , Dorothee Nickles , Kim Newton , Joshua D Webster

Réseau de co-auteurs

Joshua D Webster 10 collaborations

Vishva M Dixit 10 collaborations

Kim Newton 9 collaborations

Merone Roose-Girma 7 collaborations

Zora Modrusan 6 collaborations

Allie Maltzman 4 collaborations

Debra L Dugger 4 collaborations

Benjamin Haley 4 collaborations

Alexander F Schubert 3 collaborations

Nobuhiko Kayagaki 3 collaborations

Yue Zhang 3 collaborations

Alexander D Gitlin 2 collaborations

Klaus Heger 2 collaborations

Christopher M Rose 2 collaborations

Donald S Kirkpatrick 2 collaborations

Yuxin Liang 2 collaborations

Victoria C Pham 2 collaborations

Qingling Li 2 collaborations

Wendy Sandoval 2 collaborations

Donghong Yan 2 collaborations

Juan Zhang 2 collaborations

Jing Kang 2 collaborations

Roger Caothien 2 collaborations

Min Xu 2 collaborations

Brent S McKenzie 2 collaborations

Wyne P Lee 2 collaborations

Bettina L Lee 2 collaborations

Irma B Stowe 2 collaborations

Opher S Kornfeld 2 collaborations

Karen O'Rourke 2 collaborations

Sarah Kummerfeld 2 collaborations

Vicky Cho 2 collaborations

T Daniel Andrews 2 collaborations

Lucy X Morris 2 collaborations

Christopher C Goodnow 2 collaborations

Edward M Bertram 2 collaborations

Katherine E Wickliffe 2 collaborations

Yuzuka Kanno 1 collaboration

Linsey J Wierciszewski 1 collaboration

Homer Pantua 1 collaboration

Sharookh B Kapadia 1 collaboration

Seth F Harris 1 collaboration

Ada Ndoja 1 collaboration

Seung-Hye Lee 1 collaboration

Hai Ngu 1 collaboration

Ying-Jiun Jasmine Chen 1 collaboration

Vineela Gandham 1 collaboration

Luke Xie 1 collaboration

Giovanni Luchetti 1 collaboration

Justin L Roncaioli 1 collaboration

Roberto A Chavez 1 collaboration

Eric M Kofoed 1 collaboration

Tommy K Cheung 1 collaboration

Isabelle Lehoux 1 collaboration

Elizabeth Skippington 1 collaboration

Janina Reeder 1 collaboration

Man Wah Tan 1 collaboration

Russell E Vance 1 collaboration

Mona Abed 1 collaboration

Erik Verschueren 1 collaboration

Hanna Budayeva 1 collaboration

Peter Liu 1 collaboration

Sarah K Kummerfeld 1 collaboration

Sarah Gierke 1 collaboration

Mike Reichelt 1 collaboration

Keith R Anderson 1 collaboration

Robert J Newman 1 collaboration

Hazal Pektas 1 collaboration

Emin Maltepe 1 collaboration

Nina Oberbeck 1 collaboration

Christine S Huang 1 collaboration

Søren Warming 1 collaboration

Andrew Birnberg 1 collaboration

Weng Wong 1 collaboration

László G Kőműves 1 collaboration

Kebing Yu 1 collaboration

Eric Suto 1 collaboration

Youngsu C Kwon 1 collaboration

Emily C Freund 1 collaboration

Anna Pham 1 collaboration

Natasha Bacarro 1 collaboration

Trent Hinkle 1 collaboration

Jennie R Lill 1 collaboration

Monika Dohse 1 collaboration

Kathleen M Mirrashidi 1 collaboration

Colin Watanabe 1 collaboration

Yafei Zhang 1 collaboration

Meredith S Sagolla 1 collaboration

Ashok Kumar 1 collaboration

Yuan Zhong 1 collaboration

Amelie Albrecht 1 collaboration

Pau Biak Sang 1 collaboration

Adrian Maples 1 collaboration

Zhenan Liu 1 collaboration

Vinesh Vinayachandran 1 collaboration

Chia-Fang Lee 1 collaboration

Ashutosh Kumar 1 collaboration

Jiyuan Chen 1 collaboration

Jing Xiao 1 collaboration

Bongsoo Park 1 collaboration

Jianjun Shen 1 collaboration

Bin Liu 1 collaboration

Maria D Person 1 collaboration

Kathleen M Trybus 1 collaboration

Kam Y J Zhang 1 collaboration

B Franklin Pugh 1 collaboration

Kristine E Kamm 1 collaboration

Dianna M Milewicz 1 collaboration

Xuetong Shen 1 collaboration

Prabodh Kapoor 1 collaboration

Gözde Ulas 1 collaboration

Jian Payandeh 1 collaboration

Meredith Sagolla 1 collaboration

Lisa A Miosge 1 collaboration

Jeffrey K Holden 1 collaboration

James J Crawford 1 collaboration

Cameron L Noland 1 collaboration

Stephen Schmidt 1 collaboration

Jason R Zbieg 1 collaboration

Jennifer A Lacap 1 collaboration

Richard Zang 1 collaboration

Gregory M Miller 1 collaboration

Paul Beroza 1 collaboration

Wendy Lee 1 collaboration

Jeffrey Y K Tom 1 collaboration

Rina Fong 1 collaboration

Micah Steffek 1 collaboration

Saundra Clausen 1 collaboration

Thjis J Hagenbeek 1 collaboration

Taishan Hu 1 collaboration

Zheng Zhou 1 collaboration

Hong C Shen 1 collaboration

Christian N Cunningham 1 collaboration

Meng He 1 collaboration

Mira S Chaurushiya 1 collaboration

Subhra Chaudhuri 1 collaboration

Ying-Jiun Chen 1 collaboration

Jeffrey Eastham-Anderson 1 collaboration

Shari Lau 1 collaboration

Anwesha Dey 1 collaboration

Margaret Solon 1 collaboration

Nianfeng Ge 1 collaboration

Shannon Hambro 1 collaboration

Susan Haller 1 collaboration

Jian Jiang 1 collaboration

Miriam Baca 1 collaboration

Jessica Preston 1 collaboration

Dorothee Nickles 1 collaboration