Addressing the risk domain in the long-term management of pediatric asthma.
asthma
biomarkers
children
disease management
disease progression
early intervention
risk assessment
risk management
spirometry
Journal
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
ISSN: 1399-3038
Titre abrégé: Pediatr Allergy Immunol
Pays: England
ID NLM: 9106718
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
10
09
2019
revised:
11
11
2019
accepted:
12
11
2019
pubmed:
17
11
2019
medline:
5
3
2021
entrez:
17
11
2019
Statut:
ppublish
Résumé
There is growing concern regarding the long-term outcomes of early and poorly controlled childhood asthma, either of which can potentially lead to the development of severe asthma in adults and irrecoverable loss of lung function leading to chronic obstructive pulmonary disease. These outcomes of inadequately controlled asthma should prompt a change in practice to better and/or earlier identify children at risk of adverse respiratory outcomes of asthma, to monitor disease progression, and to design intervention strategies that could either prevent or reverse asthma progression in children. The careful follow-up of spirometry over time-in the form of lung function trajectories, the application of biomarkers to assist in the diagnosis of early asthma and medication selection for these patients, as well as methods to identify patients at risk of asthma attacks-can be used to develop individualized management strategies for children with asthma. It is now time for asthma specialists to communicate this information to patients, parents, and primary care physicians and to incorporate them into routine clinical assessments of children with asthma. In time, these concepts of risk management and prevention can be refined to provide a more comprehensive approach to asthma care so as to prevent adverse respiratory outcomes from poorly controlled childhood asthma.
Identifiants
pubmed: 31732983
doi: 10.1111/pai.13175
pmc: PMC7217022
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
233-242Subventions
Organisme : Medical Research Council
ID : G9815508
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_15018
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_19009
Pays : United Kingdom
Informations de copyright
© 2019 The Authors. Pediatric Allergy and Immunology published by John Wiley & Sons Ltd.
Références
Thorax. 2018 Dec;73(12):1110-1119
pubmed: 29858277
J Allergy Clin Immunol. 2015 Jun;135(6):1457-64.e4
pubmed: 25258144
N Engl J Med. 2016 May 12;374(19):1842-1852
pubmed: 27168434
Clin Exp Allergy. 2008 Feb;38(2):246-59
pubmed: 18076708
Eur Respir J. 2011 May;37(5):1037-42
pubmed: 20693244
JAMA. 2017 Jan 17;317(3):269-279
pubmed: 28114551
Am J Respir Crit Care Med. 2017 Apr 1;195(7):854-859
pubmed: 27710010
Pediatr Pulmonol. 2018 Jun;53(S1):S171-S173
pubmed: 29906344
Lancet. 2000 Aug 12;356(9229):556-61
pubmed: 10950233
Lancet Respir Med. 2017 Dec;5(12):935-945
pubmed: 29150410
Am J Respir Crit Care Med. 2014 May 1;189(9):1101-9
pubmed: 24606581
Eur Respir J. 2017 Feb 8;49(2):
pubmed: 28179442
Br J Gen Pract. 2016 Mar;66(644):e152-7
pubmed: 26917656
Allergy. 2013 Dec;68(12):1520-31
pubmed: 24410781
J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12
pubmed: 27777180
Eur Respir J. 2019 Jan 3;53(1):
pubmed: 30578390
J Allergy Clin Immunol. 2018 Sep;142(3):773-780
pubmed: 29627424
Eur Respir J. 2018 Apr 19;51(4):
pubmed: 29563173
Am J Respir Crit Care Med. 2005 Jan 1;171(1):68-72
pubmed: 15477497
J Allergy Clin Immunol. 2017 Oct;140(4):1130-1137.e5
pubmed: 28238748
Am J Respir Crit Care Med. 2017 May 15;195(10):1399-1401
pubmed: 28504596
Nat Genet. 2014 Jan;46(1):51-5
pubmed: 24241537
JAMA. 2016 Aug 23-30;316(8):835-45
pubmed: 27552617
Lancet Respir Med. 2018 Jul;6(7):535-544
pubmed: 29628376
J Allergy Clin Immunol. 2009 Nov;124(5):921-7
pubmed: 19895984
Pneumologie. 2017 Dec;71(12):e3
pubmed: 30406626
J Allergy Clin Immunol. 2011 Jun;127(6):1505-12.e14
pubmed: 21411131
Am J Respir Crit Care Med. 2014 Jan 15;189(2):129-38
pubmed: 24283801
Environ Health Perspect. 2013 Oct;121(10):1232-8
pubmed: 23777813
Am J Respir Crit Care Med. 2008 Jul 1;178(1):74-80
pubmed: 18420969
Arch Dis Child. 1993 Jul;69(1):120-4
pubmed: 8024293
Am J Respir Crit Care Med. 2018 Dec 15;198(12):1539-1548
pubmed: 29995435
Curr Opin Pulm Med. 2012 Jan;18(1):63-9
pubmed: 22081091
Eur Respir J. 2018 Feb 14;51(2):
pubmed: 29444915
J Allergy Clin Immunol. 2010 Apr;125(4):851-857.e18
pubmed: 20371397
Am J Respir Crit Care Med. 2009 Jan 1;179(1):19-24
pubmed: 18990678
N Engl J Med. 2014 May 01;370(18):1712-1723
pubmed: 24785206
Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5485-90
pubmed: 25848009
J Allergy Clin Immunol. 2007 Nov;120(5 Suppl):S94-138
pubmed: 17983880
J Allergy Clin Immunol. 2011 Feb;127(2):382-389.e1-13
pubmed: 21195471
Pediatr Allergy Immunol. 2019 Sep;30(6):654-657
pubmed: 31120611
Pediatr Allergy Immunol. 2020 Apr;31(3):233-242
pubmed: 31732983
Pediatr Pulmonol. 2016 Aug;51(8):778-86
pubmed: 26678320
Thorax. 2006 May;61(5):376-82
pubmed: 16384881
Thorax. 2004 Jul;59(7):569-73
pubmed: 15223862
Am J Respir Crit Care Med. 2017 Dec 15;196(12):1615-1617
pubmed: 28463537
J Allergy Clin Immunol. 2009 Nov;124(5):895-902.e1-4
pubmed: 19811812
Lancet. 2008 Sep 20;372(9643):1100-6
pubmed: 18805338
PLoS One. 2018 Feb 2;13(2):e0192390
pubmed: 29394280
J Allergy Clin Immunol. 2012 Apr;129(4):974-82.e13
pubmed: 22385633
J Allergy Clin Immunol. 2017 Jun;139(6):1935-1945.e12
pubmed: 27771325
N Engl J Med. 2015 Jul 9;373(2):111-22
pubmed: 26154786
N Engl J Med. 1995 Jan 19;332(3):133-8
pubmed: 7800004
Thorax. 2010 Jan;65(1):14-20
pubmed: 19729360
Thorax. 2018 Sep;73(9):813-824
pubmed: 29871982
Clin Exp Allergy. 2005 Jul;35(7):920-5
pubmed: 16008679
Lancet. 2018 Jan 27;391(10118):350-400
pubmed: 28911920
Am J Respir Crit Care Med. 2010 Jul 15;182(2):237-45
pubmed: 20378729
Pediatr Allergy Immunol. 2019 Sep;30(6):589-597
pubmed: 30968967
Thorax. 2001 May;56(5):345-50
pubmed: 11312401
Pediatr Pulmonol. 2010 Dec;45(12):1240-5
pubmed: 20717936
Am J Respir Crit Care Med. 2009 Jul 1;180(1):59-99
pubmed: 19535666
J Allergy Clin Immunol. 2010 May;125(5):1001-1006.e1
pubmed: 20392488
J Allergy Clin Immunol. 2015 Jun;135(6):1465-73.e5
pubmed: 25794658
Arch Dis Child. 2018 Aug;103(8):729-731
pubmed: 29305357
Eur Respir J. 2012 Dec;40(6):1324-43
pubmed: 22743675
Eur Respir J. 2016 Aug;48(2):393-402
pubmed: 27230446
Respir Med. 2016 Oct;119:48-54
pubmed: 27692147
Environ Health Perspect. 2013 Nov-Dec;121(11-12):1357-64
pubmed: 24076757
JAMA. 2017 Apr 18;317(15):1577-1578
pubmed: 28418473
Curr Opin Allergy Clin Immunol. 2018 Apr;18(2):117-123
pubmed: 29406359
Eur Respir J. 2015 Sep;46(3):622-39
pubmed: 26206872
Lancet. 2006 Aug 26;368(9537):763-70
pubmed: 16935687
Am J Respir Crit Care Med. 2010 Jun 1;181(11):1200-6
pubmed: 20167852
J Allergy Clin Immunol. 2015 Oct;136(4):885-92.e2
pubmed: 25913104
Chest. 2011 May;139(5):1165-1171
pubmed: 21540215