Early anemia and neonatal morbidity in extremely low birth-weight preterm infants.

Anemia extremely low birth-weight infant intraventricular hemorrhage newborn packed red blood cells transfusion patent ductus arteriosus

Journal

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916

Informations de publication

Date de publication:
Nov 2021
Historique:
pubmed: 19 11 2019
medline: 25 9 2021
entrez: 19 11 2019
Statut: ppublish

Résumé

Extremely low birth-weight (ELBW) preterm infants remain at high risk for mortality and major morbidities, and nearly all need packed red blood cell transfusions within their first weeks of life. The overall objective of this study was to assess the association between anemia at admission to neonatal intensive care unit (NICU) with the neonatal morbidity and mortality in ELBW infants. This retrospective study was conducted on 106 patients with ELBW admitted at our level III NICU from January 2006 to December 2015. The subjects were divided into two groups: (1) patients with anemia at admission and (2) patients without anemia. Their characteristics and outcomes were compared. Statistical analysis was performed using the Statistical Package for the Social Sciences software, version 24.0 (IBM New York, USA), and a value of Of the 106 ELBW, 34 (32%) presented with anemia at admission and 72 (68%) without anemia. Anemia-naive presented mean hemoglobin at the admission of 12.8 ± 1.5 g/dl and nonanemic 16.8 ± 2.1 g/dl, In this ELBW series, the presence of anemia at admission to the NICU was associated with HS-PDA and severe IPVH. Preventive strategies for early anemia must be encouraged.

Sections du résumé

BACKGROUND BACKGROUND
Extremely low birth-weight (ELBW) preterm infants remain at high risk for mortality and major morbidities, and nearly all need packed red blood cell transfusions within their first weeks of life. The overall objective of this study was to assess the association between anemia at admission to neonatal intensive care unit (NICU) with the neonatal morbidity and mortality in ELBW infants.
METHODS METHODS
This retrospective study was conducted on 106 patients with ELBW admitted at our level III NICU from January 2006 to December 2015. The subjects were divided into two groups: (1) patients with anemia at admission and (2) patients without anemia. Their characteristics and outcomes were compared. Statistical analysis was performed using the Statistical Package for the Social Sciences software, version 24.0 (IBM New York, USA), and a value of
RESULTS RESULTS
Of the 106 ELBW, 34 (32%) presented with anemia at admission and 72 (68%) without anemia. Anemia-naive presented mean hemoglobin at the admission of 12.8 ± 1.5 g/dl and nonanemic 16.8 ± 2.1 g/dl,
CONCLUSION CONCLUSIONS
In this ELBW series, the presence of anemia at admission to the NICU was associated with HS-PDA and severe IPVH. Preventive strategies for early anemia must be encouraged.

Identifiants

pubmed: 31736385
doi: 10.1080/14767058.2019.1689948
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3697-3703

Auteurs

Gustavo Rocha (G)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.

Sandra Pereira (S)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.

João Antunes-Sarmento (J)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.

Filipa Flôr-de-Lima (F)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.
Faculty of Medicine, Porto University, Porto, Portugal.

Henrique Soares (H)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.
Faculty of Medicine, Porto University, Porto, Portugal.

Hercília Guimarães (H)

Department of Pediatrics, Neonatal Intensive Care Unit, Centro Hospitalar, Universitário São João, Porto, Portugal.
Faculty of Medicine, Porto University, Porto, Portugal.

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Classifications MeSH