Survival of bovine digital dermatitis treponemes on hoof knife blades and the effects of various disinfectants.


Journal

The Veterinary record
ISSN: 2042-7670
Titre abrégé: Vet Rec
Pays: England
ID NLM: 0031164

Informations de publication

Date de publication:
18 Jan 2020
Historique:
received: 27 03 2019
revised: 19 08 2019
accepted: 17 10 2019
pubmed: 21 11 2019
medline: 23 9 2020
entrez: 21 11 2019
Statut: ppublish

Résumé

Bovine digital dermatitis (BDD) is a painful infectious foot disease of cattle, and much evidence implicates a pathogenic role for treponemes. This study measured the survival of BDD treponemes on hoof knife blades and tested the efficacy of relevant disinfectants under laboratory conditions. Two strains of BDD treponemes were applied to hoof knife blades under aerobic conditions. Swabs were taken at different time points (10 minutes, one hour, two hours, four hours and 18 hours) and again after 20-second disinfection time with one of five disinfectants. Swabs were used directly for nested PCR to detect treponemes or inoculated for anaerobic growth, and subsequently examined using phase contrast microscopy and PCR. BDD treponeme DNA was detectable by nested PCR at all survival time points, and these organisms were culturable from hoof knives for two hours after exposure under aerobic conditions in the laboratory. Three of the five disinfectants-1 per cent volume per volume (v/v) FAM30 Treponeme viability of two hours under aerobic conditions suggests BDD treponemes could be transmitted between cows on hoof knives. It is therefore important to apply a disinfection protocol during foot-trimming; the authors have identified three common disinfectants that may be suitable.

Sections du résumé

BACKGROUND BACKGROUND
Bovine digital dermatitis (BDD) is a painful infectious foot disease of cattle, and much evidence implicates a pathogenic role for treponemes. This study measured the survival of BDD treponemes on hoof knife blades and tested the efficacy of relevant disinfectants under laboratory conditions.
METHODS METHODS
Two strains of BDD treponemes were applied to hoof knife blades under aerobic conditions. Swabs were taken at different time points (10 minutes, one hour, two hours, four hours and 18 hours) and again after 20-second disinfection time with one of five disinfectants. Swabs were used directly for nested PCR to detect treponemes or inoculated for anaerobic growth, and subsequently examined using phase contrast microscopy and PCR.
RESULTS RESULTS
BDD treponeme DNA was detectable by nested PCR at all survival time points, and these organisms were culturable from hoof knives for two hours after exposure under aerobic conditions in the laboratory. Three of the five disinfectants-1 per cent volume per volume (v/v) FAM30
CONCLUSION CONCLUSIONS
Treponeme viability of two hours under aerobic conditions suggests BDD treponemes could be transmitted between cows on hoof knives. It is therefore important to apply a disinfection protocol during foot-trimming; the authors have identified three common disinfectants that may be suitable.

Identifiants

pubmed: 31744926
pii: vr.105406
doi: 10.1136/vr.105406
pmc: PMC7029245
doi:

Substances chimiques

Disinfectants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

67

Informations de copyright

© British Veterinary Association 2019. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

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Auteurs

Amy Gillespie (A)

Infection Biology, Institute of Infection and Global Health, University of Liverpool Leahurst Campus, University of Liverpool, Neston, UK amyg@liv.ac.uk.

Stuart D Carter (SD)

Infection Biology, Institute of Infection and Global Health, University of Liverpool Leahurst Campus, University of Liverpool, Neston, UK.

Roger W Blowey (RW)

Wood Veterinary Group, Gloucester, UK.

Nicholas Evans (N)

Infection Biology, Institute of Infection and Global Health, University of Liverpool Leahurst Campus, University of Liverpool, Neston, UK.

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Classifications MeSH