One-year outcomes in a multicentre cohort study of incident rare diffuse parenchymal lung disease in children (ChILD).


Journal

Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353

Informations de publication

Date de publication:
02 2020
Historique:
received: 11 02 2019
revised: 22 10 2019
accepted: 30 10 2019
pubmed: 22 11 2019
medline: 15 8 2020
entrez: 22 11 2019
Statut: ppublish

Résumé

We performed a prospective, observational, cohort study of children newly diagnosed with children's interstitial lung disease (ChILD), with structured follow-up at 4, 8, 12 weeks and 6 and 12 months. 127 children, median age 0.9 (IQR 0.3-7.9) years had dyspnoea (68%, 69/102), tachypnoea (75%, 77/103) and low oxygen saturation (SpO

Identifiants

pubmed: 31748256
pii: thoraxjnl-2019-213217
doi: 10.1136/thoraxjnl-2019-213217
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Hydroxychloroquine 4QWG6N8QKH
Azithromycin 83905-01-5

Types de publication

Journal Article Multicenter Study Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

172-175

Investigateurs

Jayesh Bhatt (J)
Frederik Buchvald (F)
Nazan Cobanoglu (N)
Fran Child (F)
Nwokoro Chinedu (N)
Leonard Donato (L)
Ralph Epaud (R)
Ampara Escribano (A)
Achim Freihorst (A)
Atul Gupta (A)
Emma Guy (E)
Tobias Hübner (T)
Petra Kaiser-Labusch Kind-Jugend (PK)
Christiane Lex (C)
Sarah Mayell (S)
Samantha Moss (S)
Nagehan Emiralioglu (N)
Lutz Nährlich (L)
Nadia Nathan (N)
Ruth O'Reilly (R)
Nicolas Regamey (N)
Isabelle Rochat (I)
Martin Rosewich (M)
Tugbu Sismanlar (T)
Deborah Snijders (D)
Florian Stehling (F)

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: SC and VS report other from Boehringer Ingelheim, outside the submitted work; MG reports other from Vertex and Boehringer Ingelheim, outside the submitted work.

Auteurs

Steve Cunningham (S)

Centre for Inflammation Research, University of Edinburgh, Edinburgh, UK steve.cunningham@nhs.net.
Department of Respiratory and Sleep Medicine, Royal Hospital for Sick Children, Edinburgh, UK.

Catriona Graham (C)

Wellcome Trust Clinical Research Facility, Western General Hospital, Edinburgh, UK.

Morag MacLean (M)

Edinburgh Clinical Trials Unit, University of Edinburgh, Edinburgh, UK.

Paul Aurora (P)

Department of Respiratory Paediatrics, Great Ormond Street Hospital, London, UK.

Michael Ashworth (M)

Department of Paediatric Pathology, Great Ormond Street Hospital for Children NHS Trust, London, UK.

Angelo Barbato (A)

Department of Women's and Children's Health, University of Padova, Padua, Italy.

Alistair Calder (A)

Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.

Julia Carlens (J)

Department of Pediatric Pneumology, Medizinische Hochschule Hannover, Hannover, Germany.

Annick Clement (A)

Paediatric Pulmonary Department, Trousseau Hospital APHP, Sorbonne Universities and Pierre et Marie Curie University, Paris, France.

Meike Hengst (M)

Pediatric Pneumology, Hauner Children's University Hospital, Munich, Germany.

Birgit Kammer (B)

University Children's Hospital at Dr. von Haunersches Kinderspital, LMU Munich, Munich, Germany.

Nural Kiper (N)

Pediatric Pulmonology, Hacettepe University, Ankara, Turkey.

Katarzyna Krenke (K)

Department of Pediatric Pneumology and Allergy, Warszawski Uniwersytet Medyczny, Warszawa, Poland.

Kai Kronfeld (K)

IZKS Mainz, University Medical Center Mainz, Mainz, Germany.

Joanna Lange (J)

Department of Pediatric Pneumology and Allergy, Warszawski Uniwersytet Medyczny, Warszawa, Poland.

Julia Ley-Zaporozhan (J)

Institute for Clinical Radiology, University Hospital of Ludwig Maximilian University, Munich, Germany.

Andrew G Nicholson (AG)

Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UK.

Simone Reu (S)

Pathology, Ludwig-Maximilians-Universitat Munchen Medizinische Fakultat, Munchen, Germany.

Traudl Wesselak (T)

Pediatric Pneumology, Hauner Children's University Hospital, Munich, Germany.

Martin Wetzke (M)

Department of Pediatric Pulmonology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Andrew Bush (A)

Department of Respiratory Paediatrics, Royal Brompton Hospital, London, UK.

Nicolaus Schwerk (N)

Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany.

Matthias Griese (M)

Lung Research Group, Children's Hospital of Ludwig Maximilians University, Munich, Germany.

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Classifications MeSH