Negative frequency dependent selection on plasmid carriage and low fitness costs maintain extended spectrum β-lactamases in Escherichia coli.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
20 11 2019
20 11 2019
Historique:
received:
11
07
2019
accepted:
22
10
2019
entrez:
22
11
2019
pubmed:
22
11
2019
medline:
13
11
2020
Statut:
epublish
Résumé
Plasmids may maintain antibiotic resistance genes in bacterial populations through conjugation, in the absence of direct selection pressure. However, the costs and benefits of conjugation for plasmid and bacterial fitness are not well understood. Using invasion and competition experiments with plasmid mutants we explicitly tested how conjugation contributes to the maintenance of a plasmid bearing a single extended-spectrum ß-lactamase (ESBL) gene (bla
Identifiants
pubmed: 31748602
doi: 10.1038/s41598-019-53575-7
pii: 10.1038/s41598-019-53575-7
pmc: PMC6868128
doi:
Substances chimiques
Anti-Bacterial Agents
0
beta-Lactamases
EC 3.5.2.6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17211Subventions
Organisme : RCUK | Medical Research Council (MRC)
ID : MR/N013824/1
Pays : International
Références
J R Soc Interface. 2010 Jun 6;7(47):905-19
pubmed: 19940002
Proc Biol Sci. 2005 Jan 7;272(1558):79-83
pubmed: 15875573
Nat Microbiol. 2016 Sep 26;1:16175
pubmed: 27668360
ISME J. 2016 Mar;10(3):778-87
pubmed: 26505830
Front Cell Infect Microbiol. 2014 Apr 29;4:54
pubmed: 24809026
Trends Microbiol. 2001 Sep;9(9):438-44
pubmed: 11553456
Mol Microbiol. 2000 Mar;35(6):1348-59
pubmed: 10760136
Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11103-8
pubmed: 25024219
Mol Syst Biol. 2013 Aug 06;9:683
pubmed: 23917989
Science. 2012 Jul 6;337(6090):85-8
pubmed: 22767928
Science. 2009 Jan 9;323(5911):272-5
pubmed: 19131632
Indian J Med Microbiol. 2007 Jul;25(3):230-5
pubmed: 17901640
Genetics. 2003 Dec;165(4):1641-9
pubmed: 14704155
Proc Biol Sci. 2001 Jan 7;268(1462):61-9
pubmed: 12123299
Genetics. 1979 Apr;91(4):627-37
pubmed: 17248902
Evol Appl. 2015 Mar;8(3):284-95
pubmed: 25861386
Nat Ecol Evol. 2017 Dec;1(12):1950-1960
pubmed: 29038424
ISME J. 2009 Jul;3(7):761-9
pubmed: 19340086
Proc Biol Sci. 2019 Jun 26;286(1905):20191110
pubmed: 31238848
Emerg Infect Dis. 2011 Apr;17(4):645-52
pubmed: 21470454
Appl Environ Microbiol. 2009 May;75(10):3016-28
pubmed: 19304837
Genetics. 2000 Aug;155(4):1505-19
pubmed: 10924453
Heredity (Edinb). 2011 Jan;106(1):1-10
pubmed: 20332804
ISME J. 2007 May;1(1):92-5
pubmed: 18043617
J Antimicrob Chemother. 2005 Sep;56(3):544-51
pubmed: 16040624
Evol Appl. 2019 May 14;12(6):1079-1091
pubmed: 31297143
Evolution. 1988 May;42(3):425-432
pubmed: 28564005
PLoS Genet. 2016 Sep 12;12(9):e1006280
pubmed: 27618184
Antimicrob Agents Chemother. 2012 Sep;56(9):4703-6
pubmed: 22710119
mBio. 2019 Apr 23;10(2):
pubmed: 31015329
Nature. 2006 May 25;441(7092):498-501
pubmed: 16724064
Nat Commun. 2017 Nov 22;8(1):1689
pubmed: 29162798
Curr Biol. 2009 Nov 3;19(20):1683-91
pubmed: 19800234
Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8260-5
pubmed: 27385827
PLoS Med. 2017 Oct 31;14(10):e1002416
pubmed: 29088226
Microb Drug Resist. 2004 Spring;10(1):1-9
pubmed: 15140388
Antimicrob Agents Chemother. 2009 Oct;53(10):4472-82
pubmed: 19687243
J Antimicrob Chemother. 2009 Sep;64 Suppl 1:i3-10
pubmed: 19675017
Appl Environ Microbiol. 2006 Apr;72(4):2520-5
pubmed: 16597952