Dietary Bioaccumulation and Biotransformation of Hydrophobic Organic Sunscreen Agents in Rainbow Trout.
Bioaccumulation
Biomagnification
Biotransformation
Sunscreens
Toxicokinetics
Ultraviolet filters
Journal
Environmental toxicology and chemistry
ISSN: 1552-8618
Titre abrégé: Environ Toxicol Chem
Pays: United States
ID NLM: 8308958
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
13
08
2019
revised:
13
09
2019
accepted:
18
11
2019
pubmed:
22
11
2019
medline:
5
11
2020
entrez:
22
11
2019
Statut:
ppublish
Résumé
The present study investigated the dietary bioaccumulation and biotransformation of hydrophobic organic sunscreen agents, 2-ethylhexyl-4-methoxycinnamate (EHMC) and octocrylene (OCT), in rainbow trout using a modified Organisation for Economic Co-operation and Development 305 dietary bioaccumulation test that incorporated nonbiotransformed reference chemicals. Trout were exposed to 3 dietary concentrations of each chemical to investigate the relationship between dietary exposure concentration and observed accumulation and depuration. Both EHMC and OCT were significantly biotransformed, resulting in mean in vivo whole-body biotransformation rate constants (k
Identifiants
pubmed: 31749247
doi: 10.1002/etc.4638
pmc: PMC7424631
mid: NIHMS1594936
doi:
Substances chimiques
Acrylates
0
Cinnamates
0
Sunscreening Agents
0
Water Pollutants, Chemical
0
octylmethoxycinnamate
4Y5P7MUD51
octocrylene
5A68WGF6WM
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
574-586Subventions
Organisme : Intramural EPA
ID : EPA999999
Pays : United States
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : Discovery Grant
Pays : International
Informations de copyright
© 2019 SETAC.
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