Mushroom lectins in biomedical research and development.
Antiproliferative
Antiviral
Immunomodulatory
Lectins
Mushrooms
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
15 May 2020
15 May 2020
Historique:
received:
02
08
2019
revised:
19
10
2019
accepted:
21
10
2019
pubmed:
22
11
2019
medline:
4
2
2021
entrez:
22
11
2019
Statut:
ppublish
Résumé
Lectins are unique biorecognition proteins which recognize and interact with various cell surface carbohydrates/glycoproteins. These ubiquitous molecules are involved in various cell-cell interactions and can be exploited to analyze cell surface associated interactions and biological functions. Amongst fungi, lectins have been extensively explored from mushrooms as compared to microfungi or yeasts. Lectins from basidiomycetes have diverse features in terms of their physico-chemical characteristics and carbohydrate specificity. A plethora of lectins from genera Aleuria, Agrocybe, Boletus, Pleurotus, Russula, Schizophyllum, Volvariella, etc. exhibit potential applications in biomedical field. The current review summarizes the potential sources and characteristics of mushroom lectins. Potential involvement of mushroom lectin as anticancer, mitogenic, antiviral, antimicrobial, antioxidant and therapeutic agents has been discussed.
Identifiants
pubmed: 31751693
pii: S0141-8130(19)36098-2
doi: 10.1016/j.ijbiomac.2019.10.180
pii:
doi:
Substances chimiques
Anti-Infective Agents
0
Antineoplastic Agents
0
Biological Products
0
Immunologic Factors
0
Lectins
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1340-1350Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest No declaration of interest is reported by authors.