Self-Care and Pathophysiological Function in Patients with Chronic Heart Failure.
Adherence
Anemia
Heart failure
Inflammation
Renal function
Self-care
Journal
International journal of behavioral medicine
ISSN: 1532-7558
Titre abrégé: Int J Behav Med
Pays: England
ID NLM: 9421097
Informations de publication
Date de publication:
Dec 2019
Dec 2019
Historique:
pubmed:
23
11
2019
medline:
4
3
2020
entrez:
23
11
2019
Statut:
ppublish
Résumé
Self-care is assumed to benefit physiological function associated with prognosis in patients with chronic HF, but studies examining these relations are lacking. This study aims to prospectively examine the association of self-reported HF self-care with HF-associated pathophysiological markers, including renal, hematological, and immune function. Patients with chronic HF (n = 460, 66.2 ± 9.6 years, 75% men) completed questionnaires and provided blood samples at baseline and 12-month follow-up. Linear mixed models examined random intercept and fixed between- and within-subjects effects of global self-care and the individual self-care behaviors on log-transformed TNF-α, IL-6, and IL-10, the glomerular filtration rate of creatinine (GFR Self-care was independently associated with lower GFR Our findings suggest that better global self-care was associated with poorer renal function. Performing self-care behaviors such as regular exercise and medication adherence was associated with improved physiological functioning, while restriction of fluid and sodium, and the associated daily weight monitoring were associated with adverse levels of pathophysiological biomarkers.
Sections du résumé
BACKGROUND
BACKGROUND
Self-care is assumed to benefit physiological function associated with prognosis in patients with chronic HF, but studies examining these relations are lacking. This study aims to prospectively examine the association of self-reported HF self-care with HF-associated pathophysiological markers, including renal, hematological, and immune function.
METHOD
METHODS
Patients with chronic HF (n = 460, 66.2 ± 9.6 years, 75% men) completed questionnaires and provided blood samples at baseline and 12-month follow-up. Linear mixed models examined random intercept and fixed between- and within-subjects effects of global self-care and the individual self-care behaviors on log-transformed TNF-α, IL-6, and IL-10, the glomerular filtration rate of creatinine (GFR
RESULTS
RESULTS
Self-care was independently associated with lower GFR
CONCLUSION
CONCLUSIONS
Our findings suggest that better global self-care was associated with poorer renal function. Performing self-care behaviors such as regular exercise and medication adherence was associated with improved physiological functioning, while restriction of fluid and sodium, and the associated daily weight monitoring were associated with adverse levels of pathophysiological biomarkers.
Identifiants
pubmed: 31755034
doi: 10.1007/s12529-019-09822-2
pii: 10.1007/s12529-019-09822-2
pmc: PMC7524850
doi:
Substances chimiques
Biomarkers
0
Types de publication
Evaluation Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
629-644Subventions
Organisme : Nederlandse Organisatie voor Wetenschappelijk Onderzoek
ID : 453-04-004
Références
Clin Sci (Lond). 2008 Feb;114(4):313-20
pubmed: 17916064
PLoS One. 2013;8(3):e58370
pubmed: 23472188
Eur J Cardiovasc Nurs. 2014 Dec;13(6):541-8
pubmed: 24366983
Ann Behav Med. 2003 Aug;26(1):1-7
pubmed: 12867348
Rev Esp Cardiol (Engl Ed). 2016 Oct;69(10):900-914
pubmed: 27692124
Curr Opin Investig Drugs. 2003 Sep;4(9):1088-94
pubmed: 14582453
J Cardiovasc Nurs. 2011 Jul-Aug;26(4):321-8
pubmed: 21263344
Semin Nephrol. 2006 Jul;26(4):275-82
pubmed: 16949465
Curr Hematol Rep. 2003 Mar;2(2):116-21
pubmed: 12901142
Heart Fail Rev. 2008 Dec;13(4):379-86
pubmed: 18236152
Patient Educ Couns. 2014 Jan;94(1):97-102
pubmed: 24148605
Heart Fail Rev. 2010 Jul;15(4):251-73
pubmed: 19051010
Int Heart J. 2015;56(2):192-5
pubmed: 25740394
J Card Fail. 2009 Dec;15(10):864-73
pubmed: 19944363
Nat Rev Cardiol. 2016 Jun;13(6):368-78
pubmed: 26935038
J Cardiovasc Nurs. 2009 May-Jun;24(3):179-87; quiz 188-9
pubmed: 19279494
Arch Intern Med. 2001 Oct 22;161(19):2337-42
pubmed: 11606149
Congest Heart Fail. 2010 Jul;16 Suppl 1:Si-iv; quiz Svi
pubmed: 20653717
Int J Cardiol. 2010 Jun 25;142(1):65-71
pubmed: 19167768
Arch Intern Med. 2004 Nov 22;164(21):2315-20
pubmed: 15557409
J Mem Lang. 2013 Apr;68(3):
pubmed: 24403724
Ann Intern Med. 1999 Mar 16;130(6):461-70
pubmed: 10075613
AIDS Behav. 2005 Mar;9(1):103-10
pubmed: 15812617
Biol Psychol. 2013 Feb;92(2):220-6
pubmed: 23085133
Eur J Clin Pharmacol. 2001 Apr;57(1):77-83
pubmed: 11372597
Int J Cardiol. 2014 Feb 15;171(3):368-76
pubmed: 24398230
Am J Cardiol. 2013 Apr 15;111(8):1187-91
pubmed: 23375730
Eur J Heart Fail. 2016 Aug;18(8):891-975
pubmed: 27207191
Eur J Heart Fail. 2009 Jan;11(1):99-105
pubmed: 19147463
Curr Heart Fail Rep. 2010 Mar;7(1):35-41
pubmed: 20425495
J Card Fail. 2015 Jun;21(6):439-45
pubmed: 25727486
Curr Cardiol Rep. 2012 Jun;14(3):265-75
pubmed: 22437374
Inflammation. 2012 Apr;35(2):509-15
pubmed: 21556736
Heart. 2007 Jul;93(7):814-8
pubmed: 17344329
Can J Cardiol. 2015 Feb;31(2):195-202
pubmed: 25661554
J Card Fail. 2011 Apr;17(4):325-30
pubmed: 21440871
Circ Res. 2015 Jul 3;117(2):207-19
pubmed: 26139859
J Interferon Cytokine Res. 1998 Aug;18(8):555-9
pubmed: 9726435
Circ Res. 2015 Mar 13;116(6):1046-57
pubmed: 25767289
Qual Life Res. 2006 Mar;15(2):191-201
pubmed: 16468076
Aging Dis. 2012 Feb;3(1):130-40
pubmed: 22500274
Am J Kidney Dis. 2007 Feb;49(2 Suppl 2):S12-154
pubmed: 17276798
Nephrol Dial Transplant. 2002;17 Suppl 11:39-43
pubmed: 12386257
Patient Educ Couns. 2010 Mar;78(3):297-315
pubmed: 20202778