Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds.
Acute-Phase Reaction
Animals
Cattle
Cattle Diseases
/ blood
Cross-Sectional Studies
Dairying
Dichelobacter nodosus
/ pathogenicity
Disease Outbreaks
/ veterinary
Female
Finland
/ epidemiology
Foot Diseases
/ blood
Fusobacterium necrophorum
/ pathogenicity
Gram-Negative Bacterial Infections
/ blood
Hoof and Claw
/ microbiology
Severity of Illness Index
Sheep
Sheep Diseases
/ blood
Acute phase response
Albumin
Foot rot
Foul-in-the-foot
Haptoglobin
Infectious hoof disease
Interdigital necrobacillosis
Interdigital phlegmon
Serum amyloid A
Journal
Comparative immunology, microbiology and infectious diseases
ISSN: 1878-1667
Titre abrégé: Comp Immunol Microbiol Infect Dis
Pays: England
ID NLM: 7808924
Informations de publication
Date de publication:
Feb 2020
Feb 2020
Historique:
received:
19
06
2019
revised:
13
10
2019
accepted:
23
10
2019
pubmed:
23
11
2019
medline:
10
10
2020
entrez:
23
11
2019
Statut:
ppublish
Résumé
Several Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 203 sampled cows, 60 suffered from acute stage IP. We demonstrated that acute phase response of bovine IP was evident and therefore an appropriate analgesic should be administered in the treatment of affected animals. The response was most apparent in herds with high morbidity in IP and with a bacterial infection comprising Fusobacterium necrophorum and Dichelobacter nodosus, indicating that combination of these two bacterial species affect the severity of the disease.
Identifiants
pubmed: 31756638
pii: S0147-9571(19)30172-9
doi: 10.1016/j.cimid.2019.101375
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101375Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.