Myxedema coma: four patients diagnosed at the Internal Medicine Department of the Dr. Negrin University Hospital in Spain.
Myxedema coma
hormone replacement therapy
hypothyroidism
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2019
2019
Historique:
received:
17
05
2019
accepted:
26
08
2019
entrez:
26
11
2019
pubmed:
26
11
2019
medline:
26
12
2019
Statut:
epublish
Résumé
Myxedema coma is a rare complication of hypothyroidism. Clinical examination may reveal hypotension, bradycardia, and hypothermia. Laboratory tests may show hyponatremia, lipid disorders, and elevations of creatine kinase, liver, and cardiac enzymes. We describe four cases diagnosed in our hospital during the period 1999-2017. The patients were related to amiodarone treatment, noncompliance with hormone replacement therapy, or a new diagnosis of hypothyroidism. Intravenous hormone replacement therapy was effective in three of the cases and one died. The outcome of this disease may be fatal as seen in one of our cases.
Identifiants
pubmed: 31762876
doi: 10.11604/pamj.2019.34.7.19164
pii: PAMJ-34-7
pmc: PMC6850735
doi:
Substances chimiques
Amiodarone
N3RQ532IUT
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
7Informations de copyright
© Noel Lorenzo Villalba et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
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