Vocal and motor behaviors as a possible expression of gastrointestinal problems in preschoolers with Autism Spectrum Disorder.
Abdominal pain
Constipation
Diarrhea
Gastroesophageal reflux
Sleep problems
Journal
BMC pediatrics
ISSN: 1471-2431
Titre abrégé: BMC Pediatr
Pays: England
ID NLM: 100967804
Informations de publication
Date de publication:
29 11 2019
29 11 2019
Historique:
received:
08
07
2019
accepted:
19
11
2019
entrez:
30
11
2019
pubmed:
30
11
2019
medline:
18
11
2020
Statut:
epublish
Résumé
Gastrointestinal (GI) problems are one of the most frequent comorbidities in Autism Spectrum Disorder (ASD) but can be under-recognized due to the concomitant communication difficulties of this population. Accordingly, some associated behaviors (AB) such as verbal and motor behaviors (VB and MB, respectively) have been identified as a possible expression of an underlying GI problem and evaluated through an ad hoc questionnaire (the Associated Behaviors Questionnaire -ABQ-). The aims of this study were to investigate the presence and the type of AB in an Italian sample of ASD preschoolers, and to determine their correlations with GI problems. We included 85 ASD preschoolers (mean age 4.14 years; SD 1.08) splitted into two groups (GI and No-GI) through the GI Severity Index instrument. AB were evaluated through the ABQ that includes VB, MB and Changes in overall state (C) clusters. Specific tools were administered to evaluate the ASD core ad associated symptoms, as well as the intellective and adaptive functioning. The GI group (N = 30) showed significantly higher scores in all the three ABQ areas (VB, MB and C) than the No-GI group (N = 55), with a positive correlation between GI symptoms and some specific AB as well as ABQ Total score. By dividing the whole sample in verbal and non-verbal individuals, both specific and shared AB emerged in the two groups. Our results alert clinicians to consider behavioral manifestations as a possible expression of GI problems in ASD subjects. Therefore, the evaluation of AB may be useful to identify the presence of GI problems in the ASD populations, and especially in non-verbal ASD children.
Sections du résumé
BACKGROUND
Gastrointestinal (GI) problems are one of the most frequent comorbidities in Autism Spectrum Disorder (ASD) but can be under-recognized due to the concomitant communication difficulties of this population. Accordingly, some associated behaviors (AB) such as verbal and motor behaviors (VB and MB, respectively) have been identified as a possible expression of an underlying GI problem and evaluated through an ad hoc questionnaire (the Associated Behaviors Questionnaire -ABQ-). The aims of this study were to investigate the presence and the type of AB in an Italian sample of ASD preschoolers, and to determine their correlations with GI problems.
METHODS
We included 85 ASD preschoolers (mean age 4.14 years; SD 1.08) splitted into two groups (GI and No-GI) through the GI Severity Index instrument. AB were evaluated through the ABQ that includes VB, MB and Changes in overall state (C) clusters. Specific tools were administered to evaluate the ASD core ad associated symptoms, as well as the intellective and adaptive functioning.
RESULTS
The GI group (N = 30) showed significantly higher scores in all the three ABQ areas (VB, MB and C) than the No-GI group (N = 55), with a positive correlation between GI symptoms and some specific AB as well as ABQ Total score. By dividing the whole sample in verbal and non-verbal individuals, both specific and shared AB emerged in the two groups.
CONCLUSIONS
Our results alert clinicians to consider behavioral manifestations as a possible expression of GI problems in ASD subjects. Therefore, the evaluation of AB may be useful to identify the presence of GI problems in the ASD populations, and especially in non-verbal ASD children.
Identifiants
pubmed: 31779607
doi: 10.1186/s12887-019-1841-8
pii: 10.1186/s12887-019-1841-8
pmc: PMC6883656
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
466Références
J Autism Dev Disord. 2017 Jun;47(6):1673-1681
pubmed: 28289979
Eur Child Adolesc Psychiatry. 2017 Sep;26(9):1093-1103
pubmed: 28674760
J Pediatr. 2018 Nov;202:194-198
pubmed: 29866597
Autism Res. 2014 Jun;7(3):305-13
pubmed: 24339339
J Autism Dev Disord. 2000 Jun;30(3):205-23
pubmed: 11055457
Pediatrics. 2010 Jan;125 Suppl 1:S1-18
pubmed: 20048083
J Abnorm Child Psychol. 2013 Jan;41(1):165-76
pubmed: 22850932
Autism Res. 2012 Apr;5(2):101-8
pubmed: 22511450
Pediatrics. 2012 Nov;130 Suppl 2:S98-105
pubmed: 23118260
J Autism Dev Disord. 2012 Jul;42(7):1520-5
pubmed: 22012246
Eur J Paediatr Neurol. 2012 Nov;16(6):592-8
pubmed: 22342070
J Med Microbiol. 2005 Oct;54(Pt 10):987-91
pubmed: 16157555
JAMA Psychiatry. 2015 May;72(5):466-74
pubmed: 25806498
J Autism Dev Disord. 2019 Jan;49(1):349-362
pubmed: 30350113
J Autism Dev Disord. 2015 Sep;45(9):2704-20
pubmed: 25832801
Pediatrics. 2012 Nov;130 Suppl 2:S160-8
pubmed: 23118247
J Autism Dev Disord. 2009 Mar;39(3):405-13
pubmed: 18791817
Res Dev Disabil. 2016 Jan;48:43-52
pubmed: 26540296
J Autism Dev Disord. 2009 May;39(5):693-705
pubmed: 19082876
J Autism Dev Disord. 2014 Aug;44(8):1996-2012
pubmed: 24590409
J Autism Dev Disord. 2007 Mar;37(3):413-24
pubmed: 16897378
Autism Res. 2018 Jan;11(1):24-36
pubmed: 28856868
J Pediatr. 1999 Nov;135(5):559-63
pubmed: 10547242
J Autism Dev Disord. 2014 Jun;44(6):1425-32
pubmed: 24293040
Pediatr Neurol. 2008 Dec;39(6):392-8
pubmed: 19027584
J Autism Dev Disord. 2009 Sep;39(9):1305-20
pubmed: 19415479
Am J Psychiatry. 1995 May;152(5):772-7
pubmed: 7726318
J Autism Dev Disord. 2000 Jun;30(3):237-43
pubmed: 11055459
Autism. 2014 Jul;18(5):493-501
pubmed: 24104507
Pediatrics. 2014 May;133(5):872-83
pubmed: 24777214
J Autism Dev Disord. 2014 May;44(5):1117-27
pubmed: 24193577
J Autism Dev Disord. 2006 Nov;36(8):1053-64
pubmed: 16845577
Dig Liver Dis. 2016 Mar;48(3):248-54
pubmed: 26748423
Int J Mol Sci. 2017 Aug 01;18(8):null
pubmed: 28763023
Autism Res. 2014 Aug;7(4):501-6
pubmed: 24753336
J Child Neurol. 2008 Jan;23(1):6-13
pubmed: 18056691
J Autism Dev Disord. 2017 Nov;47(11):3574-3588
pubmed: 28861653
BMC Gastroenterol. 2011 Mar 16;11:22
pubmed: 21410934
J Dev Behav Pediatr. 2006 Apr;27(2 Suppl):S128-36
pubmed: 16685179
J Dev Behav Pediatr. 2011 Jun;32(5):351-60
pubmed: 21555957
Epidemiol Psychiatr Sci. 2018 Sep 6;:1-10
pubmed: 30187843
J Autism Dev Disord. 2013 Dec;43(12):2737-47
pubmed: 23371507