Labor epidural analgesia and the risk of postpartum depression: A meta-analysis of observational studies.


Journal

Journal of clinical anesthesia
ISSN: 1873-4529
Titre abrégé: J Clin Anesth
Pays: United States
ID NLM: 8812166

Informations de publication

Date de publication:
May 2020
Historique:
received: 24 06 2019
revised: 09 09 2019
accepted: 16 11 2019
pubmed: 1 12 2019
medline: 22 6 2021
entrez: 1 12 2019
Statut: ppublish

Résumé

This study aims to systematically review the literature to evaluate the association between labor epidural analgesia (LEA) and postpartum depression (PPD). Meta-analysis. Obstetric patients delivering vaginally with or without LEA in a hospital. This study aimed to investigate the effects of providing LEA on developing PPD. Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using the random effects model. A total of 356 full text articles were reviewed. Eleven articles studying 85,928 patients met inclusion criteria. The pooled unadjusted OR 1.03 and 95% CI (0.77, 1.37) suggest that LEA is not associated with a decreased risk of developing PPD. Labor epidural analgesia was not shown to confer protection against developing PPD according to this meta-analysis. Future studies are needed to explore whether other aspects of LEA, beyond its presence or absence, influence the onset of PPD.

Identifiants

pubmed: 31784304
pii: S0952-8180(19)30982-1
doi: 10.1016/j.jclinane.2019.109658
pii:
doi:

Types de publication

Journal Article Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

109658

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Joanna A Kountanis (JA)

Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: kountani@med.umich.edu.

Christie Vahabzadeh (C)

Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: youngcar@med.umich.edu.

Samuel Bauer (S)

Department of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, 586 Pioneer Drive, Rochester, MI 48309, United States of America. Electronic address: Samuel.Bauer@beaumont.org.

Maria Muzik (M)

Department of Psychiatry, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: muzik@med.umich.edu.

Ruth Cassidy (R)

Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: ruthcass@med.umich.edu.

Casey Aman (C)

Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: ctaman@umich.edu.

Mark MacEachern (M)

University of Michigan Taubman Health Sciences Library, 1135 Catherine Street, Ann Arbor, MI 48109, United States of America. Electronic address: markmac@umich.edu.

Melissa E Bauer (ME)

Department of Anesthesiology, University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109, United States of America. Electronic address: mbalun@med.umich.edu.

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