Labor epidural analgesia and the risk of postpartum depression: A meta-analysis of observational studies.
Analgesia
Depression
Epidural
Labor pain
Obstetrics
Postpartum
Risk factors
Journal
Journal of clinical anesthesia
ISSN: 1873-4529
Titre abrégé: J Clin Anesth
Pays: United States
ID NLM: 8812166
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
received:
24
06
2019
revised:
09
09
2019
accepted:
16
11
2019
pubmed:
1
12
2019
medline:
22
6
2021
entrez:
1
12
2019
Statut:
ppublish
Résumé
This study aims to systematically review the literature to evaluate the association between labor epidural analgesia (LEA) and postpartum depression (PPD). Meta-analysis. Obstetric patients delivering vaginally with or without LEA in a hospital. This study aimed to investigate the effects of providing LEA on developing PPD. Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated using the random effects model. A total of 356 full text articles were reviewed. Eleven articles studying 85,928 patients met inclusion criteria. The pooled unadjusted OR 1.03 and 95% CI (0.77, 1.37) suggest that LEA is not associated with a decreased risk of developing PPD. Labor epidural analgesia was not shown to confer protection against developing PPD according to this meta-analysis. Future studies are needed to explore whether other aspects of LEA, beyond its presence or absence, influence the onset of PPD.
Identifiants
pubmed: 31784304
pii: S0952-8180(19)30982-1
doi: 10.1016/j.jclinane.2019.109658
pii:
doi:
Types de publication
Journal Article
Meta-Analysis
Langues
eng
Sous-ensembles de citation
IM
Pagination
109658Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.