Low-molecular-weight chitosan relieves enterotoxigenic Escherichia coli-induced growth retardation in weaned pigs.
Animals
Chitosan
/ chemistry
Cytokines
/ blood
Dietary Supplements
Enterotoxigenic Escherichia coli
Escherichia coli Infections
/ blood
Growth Disorders
/ blood
Immunoglobulins
/ blood
Intestines
/ drug effects
Lactase
/ blood
Molecular Weight
Sucrase
/ blood
Swine
Weaning
alpha-Glucosidases
/ blood
Escherichia coli
Growth performance
Immune responses
Intestinal health
Low-molecular-weight chitosan
Weaned pigs
Journal
International immunopharmacology
ISSN: 1878-1705
Titre abrégé: Int Immunopharmacol
Pays: Netherlands
ID NLM: 100965259
Informations de publication
Date de publication:
Jan 2020
Jan 2020
Historique:
received:
23
05
2019
revised:
08
07
2019
accepted:
31
07
2019
pubmed:
1
12
2019
medline:
22
10
2020
entrez:
1
12
2019
Statut:
ppublish
Résumé
The objective of the present study was to evaluate the effects of low-molecular-weight chitosan (LMWC) on the growth performance, immune responses and intestinal health of weaned pigs challenged by enterotoxigenic Escherichia coli (ETEC). A total of 32 weaned pigs were randomly allocated to four treatments: non-challenged (fed with basal diet), ETEC-challenged (fed with basal diet) and ETEC-challenged plus 50 or 100 mg/kg LMWC supplementation, respectively. After 11 days feeding, the non-challenged pigs were infused with sterilised Luria-Bertani culture, while the remaining pigs were infused with 2.6 × 10
Identifiants
pubmed: 31784403
pii: S1567-5769(19)31108-7
doi: 10.1016/j.intimp.2019.105798
pii:
doi:
Substances chimiques
Cytokines
0
Immunoglobulins
0
Chitosan
9012-76-4
Lactase
EC 3.2.1.108
alpha-Glucosidases
EC 3.2.1.20
Sucrase
EC 3.2.1.48
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105798Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.