Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Antibodies
/ chemistry
Antigen-Antibody Reactions
Binding Sites
CD4 Antigens
/ chemistry
Cryoelectron Microscopy
HIV Envelope Protein gp120
/ chemistry
HIV Envelope Protein gp41
/ chemistry
HIV-1
/ chemistry
Humans
Models, Molecular
Protein Binding
Protein Conformation
Protein Interaction Mapping
Protein Multimerization
Receptors, CCR5
/ immunology
Tyrosine
/ analogs & derivatives
Journal
Nature structural & molecular biology
ISSN: 1545-9985
Titre abrégé: Nat Struct Mol Biol
Pays: United States
ID NLM: 101186374
Informations de publication
Date de publication:
12 2019
12 2019
Historique:
received:
11
07
2019
accepted:
29
10
2019
pubmed:
4
12
2019
medline:
13
2
2020
entrez:
4
12
2019
Statut:
ppublish
Résumé
The human immunodeficiency virus (HIV-1) envelope (Env) glycoprotein, a (gp120-gp41)
Identifiants
pubmed: 31792452
doi: 10.1038/s41594-019-0344-5
pii: 10.1038/s41594-019-0344-5
pmc: PMC6899201
mid: NIHMS1541614
doi:
Substances chimiques
Antibodies
0
CCR5 protein, human
0
CD4 Antigens
0
HIV Envelope Protein gp120
0
HIV Envelope Protein gp41
0
Receptors, CCR5
0
tyrosine O-sulfate
29166358BF
Tyrosine
42HK56048U
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1167-1175Subventions
Organisme : NIAID NIH HHS
ID : P01 AI100148
Pays : United States
Organisme : NIAID NIH HHS
ID : P50 AI150464
Pays : United States
Commentaires et corrections
Type : ErratumIn
Type : ErratumIn
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