Antibacterial activity of 1,2-dicarbonyl compounds and the influence of the in vitro assay system.
3-Deoxyglucosone (3-DG)
Antimicrobials
Escherichia coli
Glyoxal (GO)
Methylglyoxal (MGO)
Staphylococcus aureus
Journal
Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639
Informations de publication
Date de publication:
01 May 2020
01 May 2020
Historique:
received:
08
07
2019
revised:
11
11
2019
accepted:
13
11
2019
pubmed:
5
12
2019
medline:
17
3
2020
entrez:
5
12
2019
Statut:
ppublish
Résumé
The antibacterial activities of the dicarbonyl compounds glyoxal (GO), methylglyoxal (MGO), 3-deoxyglucosone (3-DG) were assessed against Gram-positive and Gram-negative pathogenic and food spoilage bacteria, both in agarised and liquid assay system. The kinetics of dicarbonyls' degradation at different antimicrobial assay conditions were studied, to determine the possible interference of the nutrient medium. In agarised assay system, GO and MGO exhibited antimicrobial activity, with higher efficacy against Gram-positive strains than Gram-negative ones. The nutrient medium reacted quickly both with GO and MGO, interfering with the antibacterial potential and the degradation kinetics indicated first-order reactions. In liquid assay system, both GO and MGO inhibited the target bacteria at concentrations significantly lower than those estimated in agarised assay system. Moreover, to the best of our knowledge, the antibacterial activity of GO and MGO against Listeria innocua, Pseudomonas fluorescens, Salmonella enterica and Bacillus cereus has not been previously reported.
Identifiants
pubmed: 31796226
pii: S0308-8146(19)32043-6
doi: 10.1016/j.foodchem.2019.125905
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Glyoxal
50NP6JJ975
Pyruvaldehyde
722KLD7415
Deoxyglucose
9G2MP84A8W
3-deoxyglucosone
EXV5374VEY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
125905Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.