Role of fasciae around the median nerve in pathogenesis of carpal tunnel syndrome: microscopic and ultrasound study.


Journal

Journal of anatomy
ISSN: 1469-7580
Titre abrégé: J Anat
Pays: England
ID NLM: 0137162

Informations de publication

Date de publication:
04 2020
Historique:
accepted: 30 10 2019
pubmed: 5 12 2019
medline: 24 3 2021
entrez: 5 12 2019
Statut: ppublish

Résumé

This study investigated the connections between the median nerve paraneural sheath and myofascial structures near it, from both macroscopic and microscopic points of view. Four samples of median nerve and surrounding tissues were excised from nine non-embalmed upper limbs for microscopic analysis. Ultrasound images were analysed in 21 healthy subjects and 16 carpal tunnel syndrome patients to evaluate median nerve transversal displacement during finger motion at carpal tunnel and forearm levels. An anatomical continuity between epimysium and paraneural sheath and a reduction of paraneural fat tissue from proximal to distal was found in all samples. Median nerve displacements at both levels were significantly reduced in carpal tunnel syndrome subjects (P < 0.001). It was observed that the median nerve is not an isolated structure but is entirely connected to myofascial structures. Therefore, unbalanced tension of epimysial fasciae can affect the paraneural sheath, limiting nerve displacement, and consequently this must be included in carpal tunnel syndrome pathogenesis.

Identifiants

pubmed: 31797384
doi: 10.1111/joa.13124
pmc: PMC7083567
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

660-667

Informations de copyright

© 2019 Anatomical Society.

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Auteurs

Carla Stecco (C)

Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy.

Federico Giordani (F)

Department of Physical and Rehabilitation Medicine, University of Padua, Padua, Italy.

Chenglei Fan (C)

Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy.

Carlo Biz (C)

Department of Surgery, Oncology and Gastroenterology, Orthopedic Clinic, University of Padua, Padua, Italy.

Carmelo Pirri (C)

Physical and Rehabilitation Medicine, Department of Clinical Sciences and Translation Medicine, 'Tor Vergata' University, Rome, Italy.

Anna Chiara Frigo (AC)

Biostatistics, Epidemiology and Public Health Unit, Department of Cardiac, Thoracic and Vascular Sciences, University Hospital of Padua, Padua, Italy.

Caterina Fede (C)

Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy.

Veronica Macchi (V)

Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy.

Stefano Masiero (S)

Department of Physical and Rehabilitation Medicine, University of Padua, Padua, Italy.

Raffaele De Caro (R)

Department of Neurosciences, Institute of Human Anatomy, University of Padua, Padua, Italy.

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